علمُ الأحياء الجزيئي هو العلم الذي يَحكي قصة الجزيئات التي تُشكِّل الحياة، والتفاعلات بينها، وكيفية التحكم في هذه التفاعلات. وتطبيقاتُ علم الأحياء الجزيئي متسعةٌ للغاية، وآخذةٌ في الازدياد؛ إذ يُمكِن في الوقت الحالي تسخير قوة هذا العلم في علاجِ الأمراض، وحلِّ الجرائم، ورسمِ خريطةٍ للتاريخ البشري، وإنتاجِ كائنات ومحاصيل معدَّلة وراثيًّا. يتناول الكتابُ بدايةَ هذا العلم منذ اللَّبِنات الأساسية التي وضعها «داروين» و«والاس» و«مندل»، واكتشاف بِنية الحمض النووي في عام ١٩٥٣، ويُغطي مجموعةً واسعةً من تطبيقاته في الوقت الراهن، بما في ذلك تطوير عقاقير جديدة، وتحديد البصمات الوراثية.
I was totally absorbed by this. It reads like a detective story: DNA, RNA, proteins - what else is required for a person with a good sense of fun:-) Well, on a more serious note, if you are interested to get some initial understanding how all of this works and interacts, it is not a bad place to start. Life sciences are developing rapidly and are taking progressively more sophisticated role around and more alarmingly within us. They are on the front line of vaccine developing, gene therapies, GMOs and all that up to designer babies (God forbid) and antibiotic resistance. Basically they are everywhere. So it is good idea to have some grasp of the topic. But now I am properly interested. I need to look for a next book which would tell me more, but hopefully without me requiring a course of biochemistry... But then, why not?
This book has some interesting facts and is a good introduction to molecular biology and DNA. If you are not interested in the subject you probably should not read the book. In some parts it did not really keep my attention.
This is a great publication, considering the format. These authors in my opinion managed to get quite close to what I'd consider to be 'the ideal level of coverage' for books of this nature.
However, although I understand its goal to be brief, it occasionally throws out some terms, concepts, or abbreviations without explaining what they are (e.g. it didn't bother to explain that "kb" stands for "kilobases"). Also, there are occasionally little things that seem a bit off or not very clear. For example, the book says that Calgene created the Favr Savr tomato by "knocking out the expression of the gene coding for the enzyme endo-polygalacturonase [PG]..." (89). This makes it sound like they knocked out the gene or shut off its expression, when, in fact, they left it intact but inserted an antisense PG gene that would produce mRNA complementary to the PG mRNA, thereby interfering with the PG protein production.
But, overall, this is quite an informative and educational book that touches upon many intriguing topics. And I think it would be a good read for anyone interested in exploring the wide range of molecular biology topics/applications (and has at least a little bit of knowledge in biology).