When I've started reading it, I was wondering - so, is it the time, will this one be the first non-awesome PragProg's book on Elixir (+its landscape)? The answer is simple: we have to wait longer, the book is top notch.
I didn't consider myself to be a world-class expert, but the word "capable" was far more natural (for me to describe myself), but I have to admit I've still learned some new stuff. Even if this book doesn't assume any prior experience with Ecto, I didn't feel bored and I haven't skip any part - quite the contrary. The book is well written, samples and examples are far from being boring, I haven't identified any explicit sub-topics I'd put in the book. Obviously, there's ALWAYS something to add, but you shouldn't go over-the-board with book's size: it may appear too intimidating for beginners.
I've honestly spent some time thinking about potential issues/drawbacks, but nothing non-trivial came to my mind. If you're about to write Elixir code that accesses RDBMSes, this book is a real help. Unconditionally recommended.