The end of chapter summaries can make this a quick read, but the overall lack of endnotes can distract into the web searches. A medical doctor tried to write a popular book and succeeded in entertaining and — of course given the topic —reassuring, but lost a little too much medical rigor for me. Even though only 300 conversational pages, the text repeats itself and needs re-editing. 4 stars since profoundly accurate on advice, and in the end, eminently useful despite its flaws and lack of polish. I deeply regret that when I was younger, I completely fell for and even spoke favorably of, the calorie is a calorie dogma.
The initial “why” section of aging, feels highly original and creative to me.
The small collection of recipes at the end clearly reveal to me the author’s overall wisdom, and make me want to think twice about the areas of the book on which I initially disagree with him, such as the clinical effectiveness of metformin or rapamycin. (p256-7)
“What do you want to be 120 and still look like you were 30, with the same level of fitness, health, and vigorous a 30-year-old? […] As we have seen, the latter scenario may not be as far-fetched as it seems, when cross-link breakers, anti-aging vaccines, telomere therapies, stem cell therapy, lysosomal enzymes, and other therapies become available.” (p218)
“every day, thousands of billions of mitochondria in our body produce about 55 pounds of ATP!” (p99)
The references/endnotes are inadequate, since many assertions in the text are both novel and non-intuitive, so could use further support or data or reading. Author also has a tendency to create longish lists of one word examples, which may all be truly nuanced, but don’t help me see how each element in the list is a valid/useful example. Eg “these are nutrients like flavonoids, stilbenes, coumarins, isothiocyanates, indoles, omega-3 fatty acids, carotenes, lutein, and prebiotic fiber“ (p134)
“Research shows that want to study is paid for or sponsored by the food industry, there is an eight times greater chance that the results are positive for the food industry.” (P170). Corporate food and big food, especially for America but also in Europe increasingly, are truly evil players in this.
“Dr. Richard Kahn, scientific and medical director for the American diabetes Association, commented: ‘there is not an iota of proof that sugar has anything to do with developing diabetes.’” (P172)
A frustrating falls platitude: “as a result, for many years now we often receive outdated, week, and efficient, and conflicting health and nutrition recommendations.[…] We cannot continue to underestimate the power and great importance of healthy nutrition and healthy lifestyle in general. As a society, we need to realize that it is ultimately the consumer who has the power. As consumers we need to be critical“ (p174)
More speculative sections on cryotherapy, lysosome enzymes, and mitochondrial health are completely useless. Were sources cited you could follow them, but much better exists than what the author has read. Also true of the entire fourth section, which fortunately is short. The recipes in section 5 make up for it!