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When Germs Travel: Six Major Epidemics That Have Invaded America and the Fears They Have Unleashed

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The struggle against deadly microbes is endless. Diseases that have plagued human beings since ancient times still exist, new maladies like SARS make their way into the headlines, we are faced with vaccine shortages, and the threat of germ warfare has reemerged as a worldwide threat.

In this riveting account, medical historian Howard Markel takes an eye-opening look at the fragility of the American public health system. He tells the distinctive stories of six epidemics–tuberculosis, bubonic plague, trachoma, typhus, cholera, and AIDS–to show how how our chief defense against diseases from other countries has been to attempt to deny entry to carriers. He explains why this approach never worked, and makes clear that it is useless in today’s world of bustling international travel and porous borders.

Illuminating our foolhardy attempts at isolation and showing that globalization renders us all potential inhabitants of the so-called Hot Zone, Markel makes a compelling case for a globally funded public health program that could stop the spread of epidemics and safeguard the health of everyone on the planet.




From the Trade Paperback edition.

245 pages, Kindle Edition

First published May 11, 2004

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About the author

Howard Markel

17 books79 followers
Howard Markel, M.D., Ph.D., is the George E. Wantz Distinguished Professor of the History of Medicine, professor of pediatrics and communicable diseases, professor of psychiatry, and director of the Center for the History of Medicine at the University of Michigan. His books include the award- winning Quarantine! and When Germs Travel. His articles have appeared in The New York Times, The New England Journal of Medicine, and The Journal of the American Medical Association. A member of the Institute of Medicine of the National Academy of Sciences, Markel lives in Ann Arbor, Michigan."

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Displaying 1 - 30 of 53 reviews
Profile Image for Teri.
763 reviews95 followers
September 28, 2020
A fascinating look at six diseases that have entered the United States and the paths they took to get here. Markel, a doctor and a professor of historical medicine takes a detailed look at tuberculosis, the bubonic plague, trachoma, typhus, AIDS, and cholera through the eyes of immigrants who have come to the US with these diseases. Each chapter follows a different immigrant and different disease.
Whereas each of these people was not the first to bring these diseases to the US, their stories show how easily the pathogens can travel throughout the world.

Markel's prose is very readable. He is able to explain each disease in layman's terms and weaves it all in stories of these immigrants that tend to tug on your heartstrings. Some stories end well, others not so much. There are many pictures scattered throughout that give the reader a visual reference to the historical significance of these diseases.

This is an amazing read that will stay with me for some time, especially as we deal with COVID-19.
Profile Image for Jennifer Collins.
Author 1 book41 followers
February 25, 2017
Markel's work here is not just about what the title proclaims--and in fact, I imagine that's led to some disappointed readers--instead, it is as much about history, immigration into America, and fear as it is about disease, science, or epidemics. Yet, in bringing all of these topics together, it's a powerful look into the subjects and into the way populations have come to understand a variety of diseases which we're still working against today.

By splitting the book into six different chapters to match up with six separate diseases, Markel works to first explain a disease and where it actually may have begun (or sometimes, where it definitely didn't begin, despite popular thought), and then to dissect the understanding that culture came to about the same -- often, the understandings don't match up with history or truth, of course. And through case studies and discussions of how truth has been twisted or scarred in relation to each disease, many things become clearer, from why the popular understanding might have been shaped to allow for (or even promote) xenophobia and prejudice, on to what contemporary readers might best understand and fear about a disease, as opposed to what popular history or culture might suggest.

If there is a failing here, it's that Markel doesn't attempt (in more than an occasional sentence) to address whether America is like other nations (any or all) in its propensity to blame epidemics on immigrants, or whether this is a uniquely American pattern of thought. In some chapters, there are discussions of other nations/peoples blaming a given disease on another group, but the topic isn't addressed as a whole. In some ways, this is forgivable simply because Markel is admittedly an American historian, and may have felt this topic to be a far reach, but it does feel like something of a missing discussion. Also, the title and subtitle are, as suggested above, a bit misleading.

This book is as much about immigration and prejudice as it is about disease, and it is as much about the making of America as it is about epidemics. Some readers will come to this book for particular insights, based on the title, and perhaps be disappointed. Readers looking for a wider scope of understanding, though, may end up being more than pleased.

Absolutely, I'd recommend it.
Profile Image for Pancha.
1,179 reviews7 followers
November 20, 2009
This book feels more like an examination of the attitudes America holds and has held towards immigrants and disease than the diseases themselves, although there is a lot of information on the diseases. While each chapter acknowledges the public health issues of the various diseases, they also focus on how racism, ignorance, and a lack of compassion effect the immigrant communities blamed as carries for the diseases.
Profile Image for Benjamin Bryan.
Author 2 books35 followers
March 27, 2016
I enjoyed the read, but if you're going to ready anything by Dr. Markel, I would recommend "An Anatomy of Addiction" first.
Profile Image for K. Lincoln.
Author 18 books93 followers
September 20, 2013
I opened up When Germs Travel thinking I'd get a more general description about disease, vectors, bacteria, and how human culture influences transmission.

(Obviously I didn't read the subtitle)

What I got was even more interesting, and heart-breaking.

Markel tells the stories of Tuberculosis, Bubonic Plague, Trachoma, Typhus, AIDS and Cholera all through the lens of the immigrant experience.

The two stories that really hit me were the story of Haitians with AIDS caught behind barbed wire at Guantanamo Bay. As Markel details the ways the virus destroys cells from within, forcing host cells to continue replicating the virus making the host susceptible to other diseases, he juxtaposes those images with the story of one Haitian man and the horrible conditions he was forced to endure.

The other story that hit me was Typhus and the immigration and sanitation procedures set up along the Mexican-US Border between Ciudad Juarez and El Paso. Describing the bath mixture of gasoline, kerosene, etc that day laborers were enforced to endure just to cross the border (to kill typhus-bearing lice) was horrible.

So, in reality, this book taught me more about how race and prejudice contribute to questionable decisions about health care and public health more than it taught me about the science of the diseases themselves.

Very readable and engaging for me, a non-scientist, if difficult to read sometimes (not due to writing, but due to the nature of how the U.S. government has forced immigrants into quarantines and denied them needed healthcare or prevented them from entering the U.S. all in the name of public health).

Profile Image for Amy Lyden.
121 reviews
May 13, 2019
An interesting public health book covering the intersection of immigration and epidemics. In this current climate, it is good to reflect with a critical eye on our history with respect to immigration policy. This book put a human perspective on how disease shaped our policy and views of incoming people to the US. Spoiler alert: we were far too quick to accuse immigrants of being disease ridden and implement policies bounded by fear instead of rational thinking. I liked how his final story showed he too was not immune to these biases - I enjoy a self-aware author.

A great read for anyone interested in infectious disease - nothing earth shattering, but definitely engaging vignettes. Comes with the standard plea to put more energy into preventative public health, which I completely agree with.
Profile Image for Cecily.
164 reviews
March 24, 2008
This was really interesting as it combined immigration and medical anthropology. Of course every time I read about diseases I start worrying about every heart flutter, dry eye, itchy leg, etc.

The author does a great job of informing and providing the stories that make medical anthropology interesting. His writing style is clear.
Profile Image for Mary Ann.
830 reviews3 followers
May 25, 2020
Fascinating and well-written account of six major epidemics. My key take-away: We have gathered a lot of data and information about how germs travel, epidemics, and how people react to them. As a country, we just haven't applied any of those learnings consistently or well, as clearly evidenced by the current Covid-19 pandemic! Sadly true.
Profile Image for winona.
61 reviews
April 19, 2008
It's not as nail-biting as the title would have you believe. Interesting stuff, particularly the bits on disease etiology and progression, albeit kinda dry.
1 review
February 18, 2011
Man am I a sucker for a microhistory; chalk it up to the insatiable consumption of knowledge.
Profile Image for Marks54.
1,569 reviews1,226 followers
November 12, 2020
“When Germs Travel” is a 2004 book by a distinguished professor of medicine and medical history at the University of Michigan. It concerns six major epidemics that have occurred in the US (TB, Bubonic Plague, Trachoma, Typhus, AIDS, and Cholera. All of these examples have the international movement of diseases as a central feature. All of these examples also include a discussion of the medical details of the illness and how various US agencies became involved in the epidemic and what effects came from that involvement. While COVID-19 was not a featured actor in the book and did not seem to exist yet, the term “pandemic” is used throughout the book and the linkages with our current pandemic are not hard to appreciate.

This is an excellent book that will help readers trying to make sense of the current situation with COVID-19. I liked much about the book.

First, epidemics are highly varied. Adam Kucharski, in “Rules of Contagion” quotes someone to the effect that “if you have seen one pandemic, you have seen one pandemic”. That comes across strongly in this collection. Some of the best known epidemics are widely written about (Plague; AIDS) while others (Trachoma) are highly unusual in the US. Cholera and Typhus have plagued the US in the past but not recently, although they remain problems in the developing world.

Second, epidemics are very scary. A benefit of having a physician as the author of a book like this, is that the reader gets a clear and often terrifying description of how a disease works, how it develops in people, and how its kills people. These descriptions are common in books about particular disease outbreaks (for example, “The Ghost Map” about cholera in London), but collecting six examples together produces a strong effect.

Third, public health (in some form) is involved in all of these epidemics and the effects of the government trying to manage populations to achieve some public health objectives is consistently political, highly contested, and dependent on both political dimensions and an evolving state of medical knowledge. Threats to the economy and to local public welfare abound and are frequently in conflict with each other. Mistakes are frequently made and results are often very messy. Observers of US efforts to control the COVID-19 pandemic and develop medicines and vaccines will feel right at home. They may well feel a bit of “history repeating”.

Professor Markel concludes with the observation that the management of epidemics through effective public health is a continuing tension reflecting the costs and benefits of effective action. The absence of epidemics makes society complacent in that little extraordinary is demanded. During crises such as those profiled in the book, lots is demanded and it is at the point when public health is most needed that it is the most contentious and the most politically messy. Not much appears to have changed.

The book is well written and engaging.
Profile Image for Marilyn.
152 reviews4 followers
April 23, 2019
Dr. Markel's six major epidemics of the Twentieth Century:

Tuberculosis
Bubonic Plague
Trachoma
Typhus
AIDS
Cholera [I was surprised by this one. I had read about the cholera epidemics in the 1800s. Pretty gruesome. Do any Torontonians know that the northwest corner of busy and upscale Yonge and Bloor streets was once "Potter's Field", and scores of cholera victims were buried there? The bodies were taken elsewhere when the land was developed, but it still gives me the shivers when I remember it while riding the subway line between Yonge and Bay streets. What if...? The possibility of cholera in Detroit scared me, and I don't want to be an actress in a new performance of "Cholera Victims in T.O."]

His argument is that we think antibiotics have kept those plagues from North America's shores; but that is wishful thinking. We have immigrants and tourists arriving from countries who have contracted these diseases arriving by plane. By the time the bacteria and viruses show themselves, the human carriers have been in contact with scores of people. We North Americans have also been tourists or immigrants or aid workers in places where these diseases are endemic.

He is not advocating barricading out the immigrants or staying within our borders. He is advocating an international effort to battle the diseases globally, with the humanitarian and pharmaceutical aid that the first world countries can provide and the public health teaching that should cross borders. The world is getting more resistant bacteria and viruses, and what one country may get can no longer be assumed will be confined in that country.

Dr. Markel's history of the last hundred years of epidemics in the U.S. is not for the squeamish. The AIDs epidemic is in my lifetime after all.
Profile Image for Celina.
67 reviews4 followers
August 28, 2012
When Germs Travel is a wonderful journey into medical anthropology, documenting six major epidemics that have struck the United States as a result of immigration: tuberculosis, trachoma, typhus, bubonic plague, cholera, and AIDS. Markel looks compassionately upon how abysmal homeland conditions and travel conditions exacerbated these epidemics, as well as how the American reaction to the epidemics resulted in policy changes throughout the last century.

It's a fascinating read, and it leaves the reader with much food for thought.

My favorite exerpt:

"Beyond the cultural differences that must be bridged in any international effort, combined with factors of national politics, priorities, and values, we continue to grapple with the essential paradox of public health that began our discussion: when the system is working effectively, it is a silent venture and there are relatively few outbreaks of disease. These very successes lead most of us down a complacent path of false confidence, apathy, and assumptions that the endless dance is over. To complicate matters further, microbes themselves are hardly monolithic or permanently settled beings. For every attempt we make to destroy or weaken them, they respond with an equal and opposite force. The goal of both sides is to assume leadership of the evolutionary waltz ever in progress."

Profile Image for Maria.
365 reviews18 followers
November 12, 2015
Dr. Markel's manages to do what the best nonfiction writers do when they tackle topics too terrifying or foreign to deal with - he puts a human face on six epidemics of contagious disease that have affected American lives. In six chapters - one for each of the six epidemics - he introduces us to diseases and the immigrant and domestic lives they've affected. And he introduces us to ourselves.

My main takeaway from this book is that people - perhaps especially Americans - are too often fearful and shortsighted when the situation at hand requires courage and long-term vision. Not a terribly shocking revelation, but rather a really important reminder in a political era where Ebola made headline news for months on end and candidates for president openly advocate deporting 11 million immigrants and building a wall on our southern border.

Dr. Markel will visit the Baldwin Public Library in Birmingham, Michigan on Saturday, November 21st at 3:00 PM to deliver a talk based on this book, and you should totally come because I guarantee you it will be brilliant, compassionate, funny, and informative. Just like the book!
Profile Image for TBML.
121 reviews2 followers
June 5, 2009
With current events what they are, it is interesting to read how the world reacted to historical outbreaks of disease. It certainly gives one perspective.

I especially enjoyed the chapter on the typhus "outbreak" in my hometown of El Paso, Texas around the turn of the 20th century. The majority of deaths that can be laid at the feet of this local outbreak had nothing to do with the disease itself but the fact that people crossing the border into the US from Mexico had a disturbing habit of bursting into flames when doused with kerosene, which border officials believed would kill the disease. And I suppose it did...in a way.
-Margaret
http://chile.las-cruces.org/search/?s...
Profile Image for Kathryn.
978 reviews3 followers
October 23, 2015
Summary: Markel walks you through epidemics that have occurred in the US since 1900 and how they have impacted both public sentiment and public health procedures.

Why I Read This: I ask our staff to have him to the library. He seemed pretty darn awesome.

Review: This may be my favorite book that I've read all year. It was fascinating. Granted, I skipped some of the parts that were like, "and this is how typhus affects your intestines". But most of the book is about the history of that disease, the history of the discovery of its epidemiology, and how it likely traveled to the US. Then a lot is about the social uproar caused by these epidemics and how the American government reacted (properly or improperly) in medical ways but mostly in human rights ways. The content was fascinating. The pace was moderate. The tone was perfect.
Profile Image for Kate .
232 reviews76 followers
May 27, 2009
When Germs Travel takes a look at 6 epidemics: bubonic plague, typhus, trachoma, HIV, tuberculosis and cholera that arose in the US in the past century or so. If you read a lot of medical history, much of the information will be old news. What may not be, however, is Markel's analysis of the role that immigrants have played in bringing illness across national boundaries, and more importantly, how much undeserved blame is laid at their feet when epidemics do strike. Markel is a fine writer; he is personable and his writing is accessible to someone without a medical background. This book is recommended to anyone interested in the history of immigration to the US or interested in epidemiological history.
Profile Image for Margaret von Fizzlewick.
79 reviews14 followers
May 19, 2009
I especially enjoyed the chapter on the typhus "outbreak" in my hometown of El Paso, Texas around the turn of the 20th century. The majority of deaths that can be laid at the feet of this local outbreak had nothing to do with the disease itself but the fact that people crossing the border into the US from Mexico had a disturbing habit of bursting into flames when doused with kerosene, which border officials believed would kill the disease. And I suppose it did...in a way. A bit drastic, though.
Profile Image for John.
507 reviews17 followers
October 6, 2012
Here are six fascinating stories of invasive diseases (to U.S. borders, that is) and how authorities endeavored to cope: TB, plague, trachoma, typhus, AIDS, cholera. Most engaging is the author’s personal account of involvement with a cholera scare in Detroit in the late 1990s. Though diseases described are now largely contained in the U.S., many (even those not of the six) remain worldwide dilemmas never to be completely conquered.
Profile Image for Jennifer.
259 reviews27 followers
August 26, 2018
3.5*

This book gives a good overview of six major epidemics that have affected America throughout its history: tuberculosis, bubonic plague, trachoma, typhus, AIDS, and cholera. When Germs Travel: Six major epidemics that have invaded America since 1900 and the fears they have unleashed is informative, but the writing is not as good, or as engaging as his book An Anatomy of Addiction. Overall, I enjoyed this read, but I don’t know if I would recommend it.
Profile Image for Mark.
52 reviews16 followers
April 29, 2012
Broken into several readable chapters, each with their own study of a disease, location, and ethnic group different from each other, yet with the common theme of nationalism against the 'other' the author's final chapter is a humble, semi humorous warning of the dangers of 'knowing too much' (or thinking you do anyway).
Profile Image for Marie.
2 reviews30 followers
February 27, 2013
I read this late at night, then didn't sleep worrying how to avoid getting TB. Not as worried about bubonic plague, typhus or cholera . . . but the TB chapter kept me awake! I will no longer shake hands with anyone, wash my hands obsessively, stay away from anyone with a cough. In fact, I think I'll never leave my home. That's the answer.
1 review
Read
January 30, 2015
Love the history provided of both the germ/disease, the places where the epidemic took place, and the lifestyles and hardships of immigrants both in their home country and upon their arrival in the US. The personal stories showed how strong and proud the individuals were and continued their battle even after they became ill.
Profile Image for Kelsey.
225 reviews6 followers
June 11, 2016
A bit on the brief side, but plenty interesting. Published in the early 2000s, I often wondered if the statistics on certain things had changed. There's also a somewhat dated obsession with the terror attacks of 9/11. Still. The author has chosen interesting examples and writes in a clear, engaging manner. I'm obsessed with epidemics, and still found plenty of new information here.
Profile Image for Sarah.
207 reviews4 followers
February 17, 2009
A very readable series of vignettes about different epidemics in America. With a view to the historical, it gives a better understanding of the present and the future of contagious disease in the US.

Profile Image for David Wen.
225 reviews1 follower
June 26, 2015
Interesting background regarding how US treated various disease, epidemics, and ultimately immigrants in the 19th and 20th century. The lack of knowledge and how far we've progressed since them is fascinating and yet disheartening at the same time.
Profile Image for Laurie Fosburgh.
74 reviews2 followers
September 21, 2015
This is a great book. Disease is linked to the experience of immigrants and racism in this country and how our public health policy is driven by the fear of the unknown and not altruism. Great read, but heartbreaking.
Profile Image for Kate Fernandez.
158 reviews4 followers
August 30, 2017
I actually read this book when taking a class led by Howard Markel at the Residential College at Michigan. It was an interesting read, for sure. But super awkward discussing a book in class that your professor wrote!
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