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128 pages, Paperback
First published January 1, 1991
For an example of complicated and uncertain, take Lewontin's lecture "All the in the Genes" in which he states in regards to the nature-vs-nurture debate that (if I'm reading this correctly) both genetics and environment play a role in intellectual capacity and other unfixed characteristics of human individuals, but that it is impossible to assign a precise statistical weight to one or the other and that even if you take two genetically identical organisms and subject then to the same environmental factors while developing, they won't necessarily turn out the same. There is no connection whatsoever between the variation that can be ascribed to genetic differences as opposed to environmental differences and whether a chance in environment will affect performance and by how much. [page 29]
The vulgar error that confuses heritability and fixity has been, over the years, the single most powerful weapon that biological ideologues have had in legitimating a society of inequality. [page 37]
These institutions [agricultural experiment stations] might be expected to develop alternative methods since they are not concerned with profit and are working at public expense... A purely commercial interest has so successfully clothed itself in claims of pure science that those claims are now taught as scientific gospel.
When we combine individual selective advantage with the possibility of kin selection and reciprocal altruism, it is hard to imagine any human trait for which a plausible scenario for its selective advantage could not be invented. The real problem is to find out whether any of these stories is true. One must distinguish between plausible stories, things that might be true, and true stories, things that actually have happened. [...] At the very minimum, we might ask whether there is any evidence that such selective processes are going on at the present, but in fact no one has ever measured in any human population the actual reproductive advantage or disadvantage of any human behavior.
First, the sociobiologist makes the assumption that homosexuals leave fewer offspring. This implies a description of human sexual behavior in which the world is divided between heterosexuals and homosexuals, one class that leaves offspring and the other that does not. This description, however, does not correspond to our knowledge of human sexuality. [...]
And an average gene that is, say, 3,000 nucleotides long will differ between any two normal individuals by about 20 nucleotides. Who’s genome, then, is going to provide the sequence for the catalog for the normal person? [...] It would be necessary to look at a large population of normal and diseased people to see if one could find some common difference between them, but even this may not happen if the disease in question has a multiple genetic cause so that different people have the same disease for different reasons, even if all those reasons are a consequence of genetic changes.
Lewontin has a few ideas he wants everyone — scientists and those outside the profession alike — to incorporate into their worldview. First, that genes do not dictate our social behaviour (i.e., against sociobiology); instead, the gene-organism-environment relationship is dialectical, with each influencing and defining the others. Second, science is a political activity: our worldview influences our experimental designs and our interpretation of the world around us.
This is the third work I have read by Lewontin, and all of them make this same case, relying on similar examples and arguments. The Dialectical Biologist is the oldest, and is a collection of several essays and chapters. The rhetoric is a little rougher around the edges, and it is at times more focused on the particular target at hand than on a general framework for understanding science. And yet, because this iteration is also written with passion and urgency, it is the one I would recommend for the scientist eager for a polemic. The Triple Helix is the most detailed and carefully constructed from a scientific perspective; the author tours us through the scientific literature to understand the relationship between the three strands of the helix: gene, organism, environment. This is the one I would recommend for scientists in general, though the political threads are more muted.
Biology as Ideology is a Massey Lecture, intentionally written for a broad audience, and it fulfills that purpose wonderfully; I would recommend it for a general audience. The ideas are polished and woven together elegantly yet conversationally. The examples are well-chosen to be illustrative and approachable. If I have a critique, it is that the author leaves unsaid what should be done now that the reader (or listener) has this newfound appreciation for dialectical biology and the political ideology of science. The worldview Lewontin introduces us to is not (only) about more accurately describing the world, but about changing it, yet that is left as an exercise for the reader.