Captain Janos Catlin has been called to the forbidding mansion of Ezra Boonton, known as the "Spider of the Street". Presumably Wall Street is meant; after all the book was published in 1932 not so long after the Great Stock Market Crash of 1929 and the onset of the Great Depression. As the story proceeds, Ezra's butler is murdered and a bit later he himself is murdered too. Captain Catlin figures out fast that a lot of the people might have motives to do the deed. There is his brother, Juan Boonton, Nurse Dora Delray, Dr. Lawes, and others. and he discovers gangland rings of dealers of narcotics. Where to start - there are more murders to come as well as kidnappings and wild chases. And the "Spider of the Street" had swindled a number of people out of their life savings - back then there were no Social Security, 401Ks, IRAs and the like.