Circulation of Blood and Other Writings

by William Harvey

If the pulsations of the arteries fan and refrigerate the several parts of the body as the lungs do the heart, how comes it, as is commonly said, that the arteries carry the vital blood into the different parts, abundantly charged with vital spirits, which cherish the heat of these parts, sustain them when asleep, and recruit them when exhausted? and how should it happen that, if you tie the arteries, immediately the parts not only become torpid, and frigid, and look pale, but at length cease even to be nourished? -from the Introduction

This seminal work of medical literature, first published in 1628, spells out in clear, lucid language how the human heart pumps blood around the body via its own exclusive circulatory route. What seems like an obvious concept to us today was in fact quite revolutionary at the time: Harvey's defiance of the medical "common knowledge" of his time laid the groundwork for all modern investigations of the circulatory system, and may be the most momentous discovery of 17th-century medicine.

This important volume also includes a series of letters from Harvey to his medical colleagues in which he defends his then-astonishing theories, plus Harvey's "The Anatomy of Thomas Parr," a fascinating 1635 report on the dissection of the corpse of "a poor farmer of extremely advanced age."

OF INTEREST TO: readers of scientific history, medical students

Genres: Science, Nonfiction, Classics

256 pages, Hardcover

First published September 1, 1977

About the author

Librarian Note: There is more than one author by this name in the Goodreads database.

William Harvey (1 April 1578 – 3 June 1657) was an English physician. He was the first to describe completely and in detail the systemic circulation and properties of blood being pumped to the brain and body by the heart, though earlier writers had provided precursors of the theory. After his death the William Harvey Hospital was constructed in the town of Ashford, several miles from his birthplace of Folkestone.

At the time of Harvey's publication, Galen had been an influential medical authority for several centuries. Galen believed that blood passed between the ventricles by means of invisible pores. According to Galen's views, the venous system was quite separate from the arterial system, except when they came in contact through the unseen pores. Arabic scholar Ibn al-Nafis had disputed aspects of Galen's views, providing a model that seems to imply a form of pulmonary circulation in his Commentary on Anatomy in Avicenna's Canon (1242). Al-Nafis stated that blood moved from the heart to the lungs, where it mixed with air, and then back to the heart, from which it spread to the rest of the body. Harvey's discoveries inevitably and historically came into conflict with Galen's teachings and the publication of his treatise De Motu Cordis incited considerable controversy within the medical community. Some doctors affirmed they would "rather err with Galen than proclaim the truth with Harvey." Galen incompletely perceived the function of the heart, believing it a "productor of heat", while the function of its affluents, the arteries, was that of cooling the blood as the lungs "...fanned and cooled the heart itself". Galen thought that during dilation the arteries sucked in air, while during their contraction they discharged vapours through pores in the flesh and skin.

Independently from Ibn Al-Nafis, Michael Servetus identified pulmonary circulation, but this discovery did not reach the public because it was written down for the first time in the Manuscript of Paris in 1546. It was later published in the theological work which caused his execution in 1553, almost all copies of which were destroyed. Pulmonary circulation was described by Renaldus Columbus, Andrea Cesalpino and Andreas Vesalius, before Harvey would provide a refined and complete description of the circulatory system.

Harvey's other major work was Exercitationes de generatione animalium, published in 1651.

The book starts with a description of development of the hen's egg. The major part is theoretical, dealing with Aristotle's theories and the work of the physicians following Galen and up to Fabricius. Finally he deals with embryogenesis in viviparous animals especially hinds and does. The treatment is generally Aristotelian and limited by use of a simple magnifying lens.

Needham claims the following achievements for this work.

His doctrine of omne vivum ex ovo (all life comes from the egg) was the first definite statement against the idea of spontaneous generation. He denied the possibility of generation from excrement and from mud, and pointed out that even worms have eggs.
He identified the citricula as the point in the yolk from which the embryo develops and the blastoderm surrounding the embryo.
He destroyed once and for all the Aristotelian (semen-blood) and Epicurean (semen-semen) theories of early embryogeny.
He settled the long controversy about which parts of the egg were nutritive and which was formative, by demonstrating the unreality of the distinction.
Wikipedia