Thank you NetGaley for providing an advanced reader copy in exchange for an honest review.
2.5 stars, generously rounded up because the author is a young scientist who decided to reach out to a lay audience during his PhD studies, and we need more people like him. However, we also need better organized scientific books for the general audience. Because while the title was an excellent hook, and the opening of the book was very intriguing, the following chapters were not clearly organized and they failed to expand much on general advice that's already easily available on most youtube channels and blogs created by experienced medical providers.
I was disappointed the author didn't take more time to define aging at a molecular level and clarify the risks inherent to circumventing aging mechanisms: most of the time we risk cancer. Sure, this was mentioned, but so quickly it's almost in passing. There was also unhealthy enthusiasm for presenting correlative studies with insufficient critical analysis. For e.g.: In the chapter "Mind over matter" the author discusses the placebo effect and mentions that people who drank a low-sugar drink experienced a spike in their blood sugar levels if they were told they drank a high-sugar drink; my question is, did the study address the possibility that the spike in blood sugar levels was caused by stress? Most people know that high-sugar drinks are unhealthy and if they experience any rise in stress hormone levels that easily explains the rising blood sugar levels. There was also a lot of talk about how viruses and bacteria cause cancer, but they are not the reason for the majority of cancers. Most cancer types are caused by bad luck (such as an accidental pro-cancerous mutation following a lot of cell divisions, or being born with a gene having a mutation or series of mutations predisposing one to cancers); second most common reason for cancers are environmental factors such as high exposure to UV and ionizing radiation, exposure to certain chemicals and infection with tumorigenic viruses and bacteria. When such examples were appropriate, the author forgot to mention (or was unaware of) the whole story. For example: yes, certain H pylori strains increase the risk of stomach cancer, but if you aggressively treat against the bacteria you increase the risk of esophageal cancer, There is increasing evidence that the stomach is normally colonized by bacteria, including H. pylori, and that removing anything except the strains that can cause cancer, or treating in the absence of symptoms, is likely to cause different problems.
The reality is that aging is complicated, The book ended up being a collection of fun facts but stuck in the end to the old, trusted and known: to prolong your life exercise, eat lots of fruits and veggies, keep your morale up; and maybe you will live long enough until you can pop a pill to live longer. Despite the engaging title, there was almost no discussion about aging in other animals. The jellyfish that ages backward? The molecular mechanisms allowing that are not discussed in the book, As a former cancer researcher now involved in cancer treatment management via my medical writer job, I learned very little new things from this book. And I was also stressing out a lot in the second half of the book about how much the author jumped around, without a clear backbone to the structure. Perhaps a lay audience interested in fun facts about aging will find it more engaging than I did.