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The Maternal Imprint: The Contested Science of Maternal-Fetal Effects

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Leading gender and science scholar Sarah S. Richardson charts the untold history of the idea that a woman's health and behavior during pregnancy can have long-term effects on her descendants' health and welfare.

The idea that a woman may leave a biological trace on her gestating offspring has long been a commonplace folk intuition and a matter of scientific intrigue, but the form of that idea has changed dramatically over time. Beginning with the advent of modern genetics at the turn of the twentieth century, biomedical scientists dismissed any notion that a mother—except in cases of extreme deprivation or injury—could alter her offspring’s traits. Consensus asserted that a child’s fate was set by a combination of its genes and post-birth upbringing.

Over the last fifty years, however, this consensus was dismantled, and today, research on the intrauterine environment and its effects on the fetus is emerging as a robust program of study in medicine, public health, psychology, evolutionary biology, and genomics. Collectively, these sciences argue that a woman’s experiences, behaviors, and physiology can have life-altering effects on offspring development.

Tracing a genealogy of ideas about heredity and maternal-fetal effects, this book offers a critical analysis of conceptual and ethical issues—in particular, the staggering implications for maternal well-being and reproductive autonomy—provoked by the striking rise of epigenetics and fetal origins science in postgenomic biology today.

318 pages, Paperback

Published November 5, 2021

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About the author

Sarah S. Richardson

6 books8 followers
Sarah S. Richardson is John L. Loeb Associate Professor of the Social Sciences at Harvard University, jointly appointed in the Department of the History of Science and the Committee on Degrees in Studies of Women, Gender, and Sexuality. She is the author of Sex Itself: The Search for Male and Female in the Human Genome.

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Profile Image for Julian.
183 reviews13 followers
November 11, 2021
I wrote a professional review of this one! https://www.nature.com/articles/d4158...

If I’m recommending, I’d solidly recommend reading the intro and Chapter 8. If you’re up for a bit more, skim a bit of chapters 2-4 and read Chapter 7.
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