This text presents an introduction to the concepts and techniques of recombinant DNA research and their dramatic results. It explores core concepts in molecular biology in a contemporary inquiry-based context, building its coverage around the landmark experiments that redefined our understanding of DNA.
In 1928, James D. Watson was born in Chicago. Watson, who co-discovered the double helix structure of DNA (deoxyribonucleic acid) at age 25, was awarded the Nobel Prize in Physiology or Medicine in 1962, along with Francis Crick and Maurice Wilkins. His bird-watching hobby prompted his interest in genetics. He earned his B.Sc. degree in zoology from the University of Chicago in 1947, and his Ph.D. from Indiana University in Bloomington in 1950. He worked with Wilkins and Francis Crick at Cavendish Laboratory in England in 1951-1953, when they discovered the structure of DNA. Watson became a member of the Harvard Biology Department in 1956, then a full professor in 1961. His book The Double Helix, which was published in 1968, became a bestseller. Watson was appointed director of Cold Spring Harbor Laboratory on Long Island in 1968, and became its president in 1994. As director of the National Center for Human Genome Research at the NIH in 1989, Watson launched the worldwide campaign to map and sequence the human genome. Watson was an outspoken unbeliever who considered that human progress had been shackled by the idea of divine fate, and that human beings should do their utmost to improve the future. In a Youngstown State University speech, Watson said, "The biggest advantage to believing in God is you don't have to understand anything, no physics, no biology. I wanted to understand" (The Vindicator, Dec. 2, 2003).
Very good for appreciating the field and understanding its fundamentals. For Instance doesn't just explain what chromosomes are, it explains why they exist
This book was a recommended text for the cell and Molecular Biology module on my Masters degree. It is very informative and a good start in understanding genes and genomes.