I read this eleven years ago (10-Nov-2011), and was not super impressed. It didn't tell me much I didn't already know, and I am not so enamored of the personalities on which the book focuses.
I worked on the worm (C elegans) for most of my professional life -- from 1984 until 2015. My first International Worm Meeting was 1985. Thus, although I was not there for most of the events recounted here, I was there shortly after, and I heard about them from people who had experienced them first-hand. Thus, I didn't read this book expecting to learn more about C elegans research and researchers -- I read it to find out what people such as Andrew Brown have to say about it all. The focus on genome sequencing feels off to me. It was a big deal when it happens, but it isn't what most worm researchers care most about. We are mostly there for the biology. We LOVE the worm itself.
I know and respect most of the people involved, some more than others, but hardly any of them as much as Brown appears to want me to.
"Worm" is an engaging book about the beginning of genome sequencing, originating from the focused study of a type of nearly-microscopic, transparent worm. It is a chronicle of a historic research effort, and an insight into how research is conducted, rather than a technical discussion of biology. Andrew Brown assumes the reader has very little knowledge of genetics, and takes care to explain (in simple terms) key topics that are necessary to understand events and their importance to the narrative.
I would have liked there to be just a little more technical discussion in the book, but the author leaves numerous footnotes and sources pointing to further reading.
Brown uses a common strategy of fitting a collection of scientific discoveries into a character-driven narrative, but the narrative itself is somewhat scattered and meandering. There are outright nonsequitors and typos, and a lot of underwhelming attempts at cleverness. The stories told are definitely interesting in places, and his inclusion of lab techs in his cast of characters is commendable, but I'm not sure this book would hold my interest for long if I weren't already interested in the subject.