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The Estrogen Window: The Breakthrough Guide to Being Healthy, Energized, and Hormonally Balanced--Through Perimenopause, Menopause, and Beyond

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In The Estrogen Window, Dr. Mache Seibel, international health expert and leading authority on women’s wellness and menopause, presents groundbreaking research that explains how every woman has a window of opportunity to begin estrogen replacement.

If begun at the right time, estrogen can lower the risk of breast cancer, heart disease, and Alzheimer’s disease, while minimizing menopausal symptoms such as hot flashes, night sweats, mood swings, lower libido, fractured sleep, brain fog, irritability, and weight gain. You’ll discover which estrogens and progestogens are the safest and how long to take them, in addition to when your estrogen window closes and it’s too late to take estrogen. You’ll also gain insight about alternatives to estrogen and how to talk with your healthcare provider about what is best for you.

The Estrogen Window will eliminate your confusion, calm your fears, and help make you a partner with your healthcare provider.

237 pages, Hardcover

First published April 12, 2016

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465 people want to read

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Mache Seibel

7 books3 followers

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5 stars
35 (33%)
4 stars
32 (31%)
3 stars
23 (22%)
2 stars
7 (6%)
1 star
6 (5%)
Displaying 1 - 25 of 25 reviews
Profile Image for Jennifer.
1,188 reviews14 followers
November 13, 2020
My knee hurts; perhaps estrogen therapy will help. My oven broke; perhaps estrogen therapy will help. The snow needs shoveling... better try estrogen therapy. For this author, there is no debate - estrogen is the solution.

It was long, boring, self-congratulating and one sided. But in the end, I do see the benefits when it’s time. And perhaps it’s time to discuss soon. There are solutions to problems and spices of health problems other than estrogen level changes that the author ignores.

The good thing is you can put narration on 1.25x
Profile Image for Nancy Widin Soper.
140 reviews
July 26, 2016
While this book would be very helpful for women going through perimenopause or who are still within the 10 year "window" after going through menopause, there is little to no helpful information for a 10+ year menopausal woman still experiencing symptoms like hot flashes, night sweats, sleeping difficulties, etc.
11 reviews
May 18, 2019
Educational

The book we have been waiting for!. Read before your next OB appointment.so u can ask questions and be informed
Profile Image for Jamie.
92 reviews
April 9, 2016
I won this book on Goodreads. Very informative for women like me in peremenopause and beyond. I remember my mother being on Premerin when the scare went out about major health risks associated with it. My mother refused to quit taking it and ended up having a stroke in her 70's at which time her doctor did take her off of it. My sister had stopped as soon as the news hit switching to an herbal supplement and now here I am starting starting to deal with the symptoms. I felt a tad better about prescribed hormone therapy after reading this book and will be discussing it with my doctor at my next appointment. I did notice that all the graphs in my copy were missing with a notation on each about being added later. There did also seem to be a bit of repetition which caused me to start skimming to the parts that interested me rather than reading every word.
3 reviews
September 8, 2024
Some good information presented in an unnecessarily long format. Use it as a reference guide. I honestly feel like it was written thinking the readers are not very intelligent and that they need to over explain or repeatedly explain concepts.
However, I definitely did get some helpful points and notes that I've written down to help me make my healthcare decisions. Just didn't need to read it cover to cover! Skimmed over the repetitive info (he's a bit obsessed with the 2002 study - we get it already!!!) and when he started to over explain. Still worth reviewing.
176 reviews22 followers
March 15, 2016
I received a copy of The Estrogen Window for an honest review.

The Estrogen Window is well researched and very informative. This book contains a wealth of information on Hormone Replacement Therapy and your Estrogen Window.

Dr. Seibel discusses Estrogen studies that were analyzed incorrectly. This book corrects those errors.

The Estrogen Window gives women the information necessary to make the right choice for themselves.

220 reviews
October 27, 2018
As it says on the cover: every woman over 40 should read this book. The information in this book is crucial to becoming educated and understanding your options when it comes to perimenopause and menpause. Don't leave it too late. If you are approaching perimenopausal, or just in meopause please, please do yourself a favour and pick this book up. Believe me, it is worth it.
Profile Image for Donna Gambino.
Author 3 books7 followers
March 8, 2018
Great read. Super informative. Especially if you are in the first 5-10 years post menopause. You need to know this stuff. But read it before so you can be ready.
405 reviews6 followers
January 7, 2021
Yeah, so, I’m reading a lot about this at the moment, at a pretty furious pace. I originally gave the book 2 stars because by the end of my fast read of this book I was fed up with the patronizing repetition- it’s like he wrote each chapter independently for an article and forgot he’d said half of it already when he compiled it into a book- as well as- mostly- the strangely dated sexist understanding of women. I’m 50, so smack in the middle of his target audience, and I felt like he was talking to a 75 year old. Hey! Buddy! I grew up in the ‘80’s, not the ‘50’s! I can’t bring myself to go back and find some of the offensive examples but they were frequent enough to make me scoff. Overall, too, the repeated message is that women absolutely NEED estrogen to avoid significant loss of health and vitality- he goes through how most systems of the body (women’s) depend on estrogen and therefore decline gravely when the body stops producing it naturally. His message is that you are idiotic, pretty much, to not take estrogen for the first 5-10 years of menopause. I don’t understand how he can reconcile this to the fact that it is natural and universal process, not a deficit- I think he believes that because women haven’t been living this long for all that long in evolutionary terms, nature hasn’t caught up. Hmmmm. At the same time, he genuinely wants to get his message across that the scare of the abandoned study that found estrogen dangerous was unwarranted, due to his analysis of faulty study design. I guess I went back and gave it three stars because he truly believes his message and has included a pretty thorough argument in favour of estrogen, so at least that side of the debate is now covered. On to the next one.
Profile Image for Curly's  Ramblings.
2,040 reviews6 followers
September 10, 2025
This book has wrong information regarding perimenopause timing - it is 7 years not 4. The author also doesn’t recognize the factual difference between progestins and bioidentical (or compounded progesterone) progesterone safety. Progestin was used in the world study that scared the bajeebers out of women. Progestin has all synthetic ingredients vs natural ingredients in the bioidentical progesterone (Mexican wild yams or soy). I’m glad I only borrowed the book from the library. Save yourself some time and trouble and go read John Lee, MD’s books on perimenopause and menopause.
Profile Image for Valeria Koopman.
Author 3 books14 followers
November 13, 2020
“I came to realize there is such a thing I call the estrogen window, the time in a woman’s life when she can most safely take estrogen and benefit from it in many ways.”
Dr. Mache Seibel guides women into the terrain of estrogen and how to use it.
The Estrogen Fix is an enlightening guide to well-being.
It was a joy to have had a conversation with Dr. Mache Seibel during a podcast interview! His presence and wisdom reflected his commitment to changing lives.
Profile Image for Laureen Solari.
118 reviews
May 7, 2024
A great book to read cover to cover or, because he references the same studies throughout, you can choose chapters you’re most interested in. I have Dr. Mary Claire Haver’s two books on order and this was a great book to complement the more updated research I’ll get from her. It’s shocking how little your PCP or GYN know about menopause. Read the studies, ladies. Demand better care.
Profile Image for EMP.
789 reviews4 followers
June 20, 2018
Good to read something with updated info. Mention HRT and people still immediately respond with "that will kill you!"
Profile Image for Ruth.
177 reviews1 follower
November 19, 2018
I didn’t know what it would be about before I started reading it — vey pro taking estrogen! I still learned a few useful things about lifestyle changes though.
Profile Image for Whitney.
23 reviews1 follower
May 8, 2019
Extremely helpful and easy to understand this complicated issue.
7 reviews
September 25, 2024
Start your research with this book! Eye opening! Lots of medical jargon and data and well written.
Profile Image for Kitten Kisser.
532 reviews21 followers
January 20, 2026
A little outdated now but ahead of it’s time when it was written.
I like that the author didn’t brush off natural alternatives to pharmaceuticals.
Overall a useful read from my local library.
34 reviews
May 19, 2024
This book was informative, but the repetition was annoying. He repeats the same basic information in every chapter. For example, he stated repeatedly that "progestin is necessary for women who still have their uterus because they are at high risk of developing uterine cancer if they take estrogen alone."

Also, I feel like for most of the book, he speaks as if the only symptoms of menopause are hot flashes and vaginal dryness (although later on he does go into the various ways menopause affects your heart, brain, and bones).

There were a couple times that I thought it was very evident that this book was written by a man, not a woman. For example, spend half a page discussing cosmetic procedures, including fillers and Botox, to make your skin appear more youthful.
Profile Image for Chelene.
12 reviews
March 11, 2016
As a perimenopausal female, I find this book to be quite informative.
My own mother is recent uterine cancer survivor and I have at least three direct female relatives who have died from complications due to other gynecological cancers.
As the author states, "You will learn about the good about estrogen, the bad about it, and most importantly, the timing of it."
Although I still haven't made any final decisions concerning hormone replacement therapy,
I now have a few more questions and topics I will bring up during my next visit with my gynecologist this summer .
I cannot be more thankful to have an opportunity to read this book. I received an ARC copy of this book through Goodreads
Profile Image for Tess.
113 reviews2 followers
March 17, 2016
I received this ARC from Goodreads Giveaways and Rodale Books. Thank you!

I found this book very helpful and wish it had been written 10 years ago when I was experiencing horrible perimenopausal symptoms. It took me six years to find a doctor that would listen to my concerns. This book is filled with information and documented scientific studies. Dr Seibel's presentation of the material is easy to understand and he covers a variety of areas that are important when considering hormonal health. It is a must read for women.
Profile Image for Susan.
966 reviews19 followers
March 19, 2016
I won this book through goodreads. I loved this book. Every woman at this "age" should give it a read.
44 reviews
May 6, 2024
My copy is 2016 publication, maybe there are mater ones? The book is really good and I would agree with the recommendation on the cover that every woman over 40 should read it.
Displaying 1 - 25 of 25 reviews

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