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Organic Chemistry

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On the cover of this book is a Pacific yew tree, found in the ancient forests of the Pacific Northwest. The bark of the Pacific yew tree produces Taxol, found to be a highly effective drug against ovarian and breast cancer. Taxol blocks mitosis during eukaryotic cell division. The supply of Taxol from the Pacific yew tree is vanishingly small, however. A single 100-year-old tree provides only about one dose of the drug (roughly 300 mg). For this reason, as well as the spectacular molecular architecture of Taxol, synthetic organic chemists fiercely undertook efforts to synthesize it. Five total syntheses of Taxol have thus far been reported. Now, a combination of isolation of a related metabolite from European yew needles, and synthesis of Taxol from that intermediate, supply the clinical demand. This case clearly demonstrates the importance of synthesis and the use of organic chemistry. It's just one of the many examples used in the text that will spark the interest of students and get them involved in the study of organic chemistry!

1344 pages, Hardcover

First published January 1, 1980

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T.W. Graham Solomons

57 books5 followers

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5 stars
136 (38%)
4 stars
102 (28%)
3 stars
67 (18%)
2 stars
26 (7%)
1 star
25 (7%)
Displaying 1 - 17 of 17 reviews
Profile Image for Adam.
127 reviews16 followers
December 2, 2009
Riddled with errors that actually teach the wrong material, but if you are made aware of these and avoid them then the book is fine.

Clear descriptions and mechanisms (multi-coloured) help with studying.
Recommended over my other Organic textbook (which sucks big ones).
Profile Image for Erfan Abedi.
66 reviews10 followers
Did Not Finish
March 28, 2022
خب اینم دیگه آخراشه، فصل 12 رو که تموم کنم می‌رم که تجزیه رو برسونم به یه جاهای خوب.
Profile Image for curry.
5 reviews
March 28, 2026
wouldn't have been able to see twice on their 5th world tour three years ago without this bad boy
5 reviews
January 25, 2017
This textbook was an amazing follow up read to a honors chemistry textbook such as Chemistry by Stephen Zumdahl. With that context in mind, I really loved reading this textbook and thoroughly exploring the complex subject of organic chemistry. The book covers everything from the basics of organic chemistry to the most complicated, intricate topics such as the biological applications of such organic chemistry. The book includes diagrams, charts, tables, is arranged in an aesthetically pleasing way, and the writing style is fluid and relatively to read. Being easy to read was a huge plus for this textbook; being interested in the material is not easy if it is a struggle to read the text. Having said this, the only complaint I have with this textbook is that it does require quite a lot of previous knowledge. This makes sense, as the subject is an advanced level of chemistry, but it does make this book not suitable for most people.
Profile Image for Mariano Hdz.
23 reviews5 followers
June 4, 2014
Im good at Chem, but I just hate it so much, I didn't work at my ap chemistry course for a whole semester and bought this book to study a week before the test and I got an awesome grade, it focuses more on different types of reactions and it's not that dense.
4 reviews10 followers
October 14, 2008
it's better to actually read than to carry all over campus for a year and counting...
1 review1 follower
Want to Read
July 12, 2012
i would like read this book
Displaying 1 - 17 of 17 reviews