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Computer Applications in Pharmaceutical Research and Development

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A unique, holistic approach covering all functions and phases of pharmaceutical research and development


While there are a number of texts dedicated to individual aspects of pharmaceutical research and development, this unique contributed work takes a holistic and integrative approach to the use of computers in all phases of drug discovery, development, and marketing. It explains how applications are used at various stages, including bioinformatics, data mining, predicting human response to drugs, and high-throughput screening. By providing a comprehensive view, the book offers readers a unique framework and systems perspective from which they can devise strategies to thoroughly exploit the use of computers in their organizations during all phases of the discovery and development process.

Chapters are organized into the following
* Computers in pharmaceutical research and a general overview
* Understanding mining complex systems for knowledge
* Scientific information handling and enhancing productivity
* Computers in drug discovery
* Computers in preclinical development
* Computers in development decision making, economics, and market analysis
* Computers in clinical development
* Future applications and future development

Each chapter is written by one or more leading experts in the field and carefully edited to ensure a consistent structure and approach throughout the book. Figures are used extensively to illustrate complex concepts and multifaceted processes. References are provided in each chapter to enable readers to continue investigating a particular topic in depth. Finally, tables of software resources are provided in many of the chapters.

This is essential reading for IT professionals and scientists in the pharmaceutical industry as well as researchers involved in informatics and ADMET, drug discovery, and technology development. The book's cross-functional, all-phases approach provides a unique opportunity for a holistic analysis and assessment of computer applications in pharmaceutics.

844 pages, Hardcover

First published June 1, 2006

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About the author

Sean Ekins

28 books

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Profile Image for loafingcactus.
499 reviews55 followers
November 23, 2011
I can't imagine any situation where I would have read this book except that it was required for a class. Given that, it covers the topic very well and as of winter 2011 is only slightly outddated. Most of the chapters in the beginning are very specific, with a lot of information on molecule identification. The last three chapters are most useful, covering the big picture of ethics and the fact that all this information isn't doing pharam as much good as one might have thought.
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