A selection of 17 papers from a March 1995 gathering held as part of a year devoted to mathematical support for molecular biology. Biochemists and computer scientists discuss protein folding, simulation and modeling techniques, heuristics, and exact algorithms for globally optimizing non-convex energy functions. Among the topics are rugged energy landscapes, a minimal principle in the phase problem of X-ray crystallography, and the rapid evaluation of potential energy functions in molecular and protein conformations. No index. Annotation copyright Book News, Inc. Portland, Or.