Amphetamine Misuse appears at the beginning of a phase in drug history that will see changes in patterns of use which will impact society as a variety of potential users; systems of health care; social control; international trade procedures, and even the economic bases of nations. It studies the nature of amphetamine use in different cultural settings, common features are identified and enigmas exposed. Greater international collaboration is needed if appropriate preventive measures are to be devised, and the sharing of information should be regarded as only a first step towards a more coordinated approach that includes social research within improved systems of national and international drug monitoring and communication.