This disk contains a complete collection of over 500 papers from the last 10 years of SPIE's Laser-Tissue Interaction conference series. Topics include laser ablation, laser-induced thermal effects, ocular effects, tissue optics, soft-tissue modeling, photothermal interactions, photochemical effects, basic and clinical research, delivery systems, immunologic mechanisms, interstitial laser photocoagulation, optoacoustic imaging and sensing, pulsed lasers, and simulation, monitoring, and clinical applications.