Anterior segment intraocular inflammation (ASII) or, as more often designates anterior uveitis (AU) is a common manifestation implying that the inflammatory processes are confined to the structures of the anterior segment of the eye. This handbook will help the practicing ophthalmologist to design a logical and clear approach for the work-up of patients with ASII. Produced under the auspices and financial support of the International Ocular Inflammation Society (IOIS). For each given patient, the most potentially yielding laboratory tests are suggested.