This fully revised and well-documented new edition of the fields standard reference integrates the latest information on the scientific basis of respiratory medicine with its current practice. The book details the scientific principles of respiratory medicine and its foundation in basic anatomy, physiology, pharmacology, pathology, and immunology to provide a rationale and scientific approach to the more specialized clinical material covered in subsequent sections. Offers most up-to-date coverage of the latest developments; including inflammation, Macrophages, Pulmonary Immunology, Inflammation, Injury Repair, and Surfactant. Reflects the advances in understanding of the anatomic basis of pulmonary physiology in normal persons and the abnormalities of structure and function that accompany disease. Describes the problems of environmental and occupational diseases.