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Quadruplex Nucleic Acids As Targets For Medicinal Chemistry (Volume 54)

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The realisation that human, animal, viral and bacterial genomes all contain over-representation of higher-order quadruplex structures in regulatory and other pharmacologically-useful regions, has led to a large number of studies aimed at exploiting this findings for therapeutic and diagnostic purposes. Quadruplex-binding small molecules are starting to be evaluated in human clinical trials.

564 pages, Hardcover

Published September 8, 2020

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