Introduction to Analytical Biotechnology

by William S. Hancock, Ira S. Krull

Introduction to Analytical Biotechnology focuses on the production of recombinant DNA-derived proteins in bacterial and mammalian cell systems. This book presents the analytical techniques and the protein chemistry underlying the production, purification, formulation, lot release, stability testing, and regulatory submissions for these protein products. Derived from lectures on analytical separations and analytical biotechnology, this text covers a wide variety of topics, including approaches to the study of protein structures, protein degradation reactions, protein aggregation, methods to measure protein heterogeneity, glycoproteins, phosphoproteins, and proteomic techniques.

384 pages, Hardcover

Published March 1, 2009