Basic plot: The oldest established, permanent floating crap game in New York needs a location, and Nathan Detroit will literally do anything to get it, including betting a notorious high roller that he can't get a date with a religious mission worker. Hilarity ensues.
This was one of my favorite performances back in high school, and I've also helped put it on now that I'm a teacher. It's a great show with lots of fun songs and great comedic opportunities. Everyone has a great time with this one, and I'd recommend it just about anywhere.