This book provides a comprehensive and integrated survey of pathogenesis and immunity in the disease pertussis, or whooping cough. The scope is wide, covering issues from the molecular biology of Bordetella pertussis, rough vaccine manufacture and testing to clinical medicine and epidemiology. The book contains 21 chapters written by 31 international, authorities and active researchers in the pertussis field. The main emphasis is on recent developments in knowledge of pertussis disease and the properties of pertussis vaccine. Each chapter contains a brief introduction for the nonspecialist.