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Neuroglia

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Glia are support cells of the nervous system, more numerous than the nerve cells themselves. In recent years it has been discovered that they have a far wider range of functions than was previously known, so this new book is very timely. This is a definitive work covering all aspects of glial
cells including glial morphology, physiology, pharmacology, biochemistry, pathology and their involvement in the pathophysiology of neurological diseases. The book is written by leaders in the field of glial research and is carefully edited to ensure consistency and thoroughness in the treatment of
each topic. A total of 69 chapters conveys in a highly readable fashion the excitement that pervades this rapidly expanding area of neurobiology. The enormous amount of new information about glial cells that is carefully summarized here leads to the inescapable realization that these cells interact
importantly with neurons in all of the brain's main functions.

1104 pages, Hardcover

First published October 19, 1995

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Helmut Kettenmann

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Profile Image for Liam O'Leary.
555 reviews145 followers
October 19, 2018
I didn't read all chapters but I made detailed summary notes on almost all the astrocyte chapters.

As a PhD student studying human astrocytes I am hesitant to recommend this or any textbook, given there haven't yet been enough studies to form a strong consensus about the structural or functional identity of just about any glial cell type.

For example, the astrocyte field currently has many disputes about general principles that are not tackled in this book as they are too new, for example: astrocytic gliotransmission, astrocyte-specific connexins, the function and specificity of astrocyte markers, and the positive or negative role of astrogliosis. Many of the chapters are filled with old 1980 papers studying primary astrocyte (not even a/n) cultures. I did not find many of the papers that I have learned to be critical to my field in the latest ebook and hardcover editions provided by my university and another (for example, by the Molofsky, Barres and Nedergaard groups).

The chapters focusing on the evolution and invertebrate glial systems were the most helpful as that literature rarely comes up in general glial discussion.

But, in short, you would be better off reading reviews if you're a specialist, and not trying if you're not a specialist, because the field is presently moving too fast and controversially for documenting useful take-home messages.
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