Computer Modeling of Chemical Reactions in Enzymes and Solutions

by Arieh Warshel

This practical reference explores computer modeling of enzyme reations--techniques that help chemists, biochemists and pharmaceutical researchers understand drug and enzyme action.

Genres: Chemistry

236 pages, Hardcover

First published November 1, 1991

Reviews

[Kevin K. Gillette · Rating 5 out of 5]

Professor Warshel, the recent recipient of the Nobel Prize in Chemistry for his work in computational chemistry methods, has written an informative and readable monograph specifically geared toward those interested in how modern chemists study tertiary and quaternary interactions between proteins and their environment.

This work assumes familiarity with physical chemistry at an intermediate level, especially the notion of mathematicsl treatments of molecular orbitals (the classic work by Ballhausen, "Ligand Field Theory," is an excellent reference for this subject) and statistical mechanics (Prof. Hecht's book on this subject is also highly recommended).

Moreover, Prof. Warshel writes in an accessible style that manages to entertain even as it informs. If you've ever wondered about how a Nobel-caliber thinker sees his work and world, this would be an ideal way to get a glimpse.