Serotonin 1a Receptors in Depression and Anxiety

by S.M. Stahl

One of the major breakthroughs in psychopharmacology has been the identification of specific serotonin receptor subtypes as targets for psychotropic drug development. This volume examines the role of one of these receptor subtypes, the serotonin 1A receptor, in anxiety, depression, and other psychiatric disorders and presents extensive preclinical and clinical studies on the azapirone serotonin 1A agonists, a new class of drugs that has shown great promise in treatment of these disorders. Leading experts assess the advantages and limitations of azapirones as anxiolytics and antidepressants and explore the potential of these agents for treatment of obsessive-compulsive disorder and impulse control disorders.

216 pages, Paperback

First published May 1, 1992