Acute Myelogenous Leukemia: Genetics, Biology and Therapy

by Lalitha Nagarajan (Editor)

The Leukemia Stem Cell.- Epigenetic Mechanisms in AML - A Target for Therapy.- Chromosomal Translocations in Detection and Prognostic Significance.- Chromosomal Deletions in AML.- Genes Predictive of Outcome and Novel Molecular Classification Schemes in Adult Acute Myeloid Leukemia.- Receptor Tyrosine Kinase Alterations in AML - Biology and Therapy.- Lineage-Specific Transcription Factor Aberrations in AML.- Proleukemic RUNX1 and CBF? Mutations in the Pathogenesis of Acute Leukemia.- Acute Myeloid Leukemia with Mutated Nucleophosmin (NPM1): Molecular, Pathological, and Clinical Features.- New Players in AML Pathogenesis.- Murine Models of Human Acute Myeloid Leukemia.- Apoptosis in Regulation and Therapeutic Targeting.- Acute Promyelocytic A Paradigm for Differentiation Therapy.- Immunotherapy of AML.- Therapy of Acute Myelogenous Leukemia in Adults.

292 pages, Paperback

First published January 1, 1992