The techniques have been applied extensively in clinical medicine but have been under-utilized by bioscientists in drug development, safety assessment, and in the early identification of the molecular mechanisms of target cell injury. Aimed at informing pharmacologists and toxicologists, the scope of this book is broad in terms of applications, including chemical distribution, pathology and oncology in different organ systems, marine pollution, and the role of calcium in cell signalling. Annotation copyright Book News, Inc. Portland, Or.