Gene Regulation: Biology of Antisense Rna and DNA

by Robert P. Erickson, Jonathan G. Izant (Editor)

This volume examines the biology of antisense (i.e., backwards genetic information) oligodeoxynucleotides, RNA, and ribozymes and explores their potential therapeutic applications, particularly for inhibition of viral replication and cancer gene expression. Leading international experts from academic institutions and industry describe new approaches to development of pharmaceuticals using antisense ribozymes, oligonucleosides, and RNA. Close attention is also given to drug approval and other practical issues involved in introducing these agents into clinical practice.

384 pages, Hardcover

First published December 1, 1991