This issue of Surgical Oncology Clinics of North America, guest edited by Dr. Chandrajit P. Raut, is devoted to Sarcomas. Dr. Raut has assembled expert authors to review the following Histologic Subtypes and Changes in the Recent WHO Classification; Distinguishing Radiologic Characteristics of Sarcoma Histologic Subtypes; Extremity Soft Tissue Tailoring Resection to Histologic Subtype; Retroperitoneal Fact, Opinion, and Controversy; Breast Sarcoma; Management of Sarcoma Metastases to the Lung; Gastrointestinal Stromal Tumor; Surgical Management and Future Targeted Therapy; Myxofibrosarcoma; Malignant Peripheral Nerve Sheath Tumor; Desmoid Evolving Treatment Standards; Dermatofibrosarcoma Surgery v. Mohs; Radiation Indications and Controversies for Neoadjuvant Therapy, Adjuvant Therapy, IORT, and Brachytherapy; Does Neoadjuvant or Adjuvant Therapy Improve Outcomes?; and more!