Atherosclerosis: Cellular and Molecular Interactions in the Artery Wall

by Sergey Fedoroff (Editor), Gary D. Burkholder (Editor), Avrum I. Gotlieb (Editor)

Rudolph Altschul: Man and Scientist.- 1 The Dynamic Vessel Wall.- Natural History of Atherosclerosis.- Adaptations of Mature and Developing Arteries to Local Hemodynamics.- The Cytoskeleton of Arterial Smooth Muscle Cells during Development, Atheromatosis and Tissue Culture.- 2 Vascular Wall Injury and Repair.- Repair of Arterial Endothelium.- The Role of the Cytoskeleton in Endothelial Repair.- Thrombin-Stimulated Endothelial Cell Functions: Monocyte Adhesion and PDGF Production.- 3 Extracellular Matrix Interactions in Atherogenesis.- Dynamic Responses of Collagen and Elastin to Vessel Wall Perturbation.- Dynamic Interaction of Proteoglycans.- Endothelial Cell - Extracellular Matrix Interactions: Modulation of Vascular Cell Phenotype by Matrix Components and Soluble Factors.- 4 Autocrine and Paracrine Control of Vascular Tissue.- Regulation of PDGF Expression in Vascular Cells.- Endothelial Regulation of Vasomotor Tone in Atherosclerosis.- Production of Cytokines by Vascular Wall Cells: An Update and Implications for Atherogenesis.- 5 Thrombosis and Fibrinolysis.- Hypoxia and Endothelial Cell Function: Alterations in Barrier and Coagulant Properties.- Regulation of Type One Plasminogen Activator Inhibitor Gene Expression in Cultured Endothelial Cells and the Vessel Wall.- Platelet Reactions in Thrombosis.- Eicosanoid Metabolism and Endothelial Cell Adhesion Molecule Expression: Effects on Platelet/Vessel Wall Interactions.- 6 Lipids in Atherogenesis.- Receptor-Mediated Low Density Lipoprotein Metabolism.- The Molecular Basis for Lipoprotein Interaction with Vascular Tissue.- Cholesterol: Is there a Consensus?.- Contributors.

292 pages, Paperback

First published June 30, 1991