Human Retroviral Infections: Immunological and Therapeutic Control

by Kenneth E. Ugen (Editor), Mauro Bendinelli (Editor), Herman Friedman (Editor)

This collection of works brings together experts in the field of human retroviral pathogenesis, vaccine development, and the clinical treatment of AIDS. One of the greatest problems facing the development of an effective vaccine against HIV-1 is the ability of the virus, particularly in the immunogenic envelope glycoprotein, to undergo amino acid hypervariability, thus making a vaccine against one envelope glycoprotein ineffective against other viruses due to their mutability.

391 pages, Kindle Edition

First published June 1, 2000