HYPOFRACTIONATION - Scientific Concepts and Clinical Experiences

by Alan Pollack M.D Ph.D

This book, formatted by disease site to contrast methods and views, is a unique compendium by hypofractionation leaders in the field. The publication is timely in providing information on scientific concepts and clinical experiences of using hypofractionated radiotherapy that includes both non-ablative hypofractionated radiation doses as well as single high-dose ablative radiotherapy. Topics that will be covered in this book include patient characteristics and selection criteria for hypofractionation schemes; analysis of different hypofractionation delivery strategies; differentiation of the types of radiation treatment algorithms for various disease site malignancies; identification of the potential for errors in tumor targeting; understanding of normal tissue toxicity; review of dose response killing effects describing the role of alpha/beta ratio; evaluation of bystander and abscopal effects; outline of hypoxia-influencing factors on response to hypofractionation schemes and enumeration of the induction of immunogenicity in tumors irradiated with hypofractionated radiotherapy.

382 pages, Hardcover

First published December 31, 2011