The book 'Python Programming for Mechanical Engineers' is a comprehensive manual that presents Python programming and its real-world applications in Mechanical Engineering. Commencing with basic Python principles in Chapter A, the guide advances to practical projects in Chapter B, including aerodynamic analysis, robotic arm kinematics, and engine data analysis, all driven by Python. It accommodates readers with diverse programming backgrounds, empowering them with necessary abilities to adeptly tackle practical engineering issues. This publication encourages readers to delve into the potent amalgamation of Python programming and Mechanical Engineering, presenting valuable understanding, tangible illustrations, and an enriching educational journey.