This outstanding volume presents the latest applied mathematical and statistical modeling research that can help focus and improve major decision-making in planning, resource allocation, and public health policy for the current AIDS health crisis. Thirty detailed chapters examine how mathematical and statistical tools are being successfully applied to many AIDS-related issues, including forecasting, evaluation of behavioral intervention programs, natural history and disease progression, clinical trials for treatment, field studies of incidence and prevalence of the disease, characterization of the disease transmission process, and evaluation of the societal costs and benefits of alternative policy decisions.