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Neuroglia

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Neuroglia is the only comprehensive reference book on the basic biology and function of glial cells. This long-awaited second edition has been completely reorganized and rewritten to include the dramatic advances in this field since the first edition was published ten years ago. The impact
of the second edition will be greater than that of the first because the majority of neuroscientists now acknowledge that neuroglia are elemental to most, if not all, brain functions. The second edition covers the entire field of glial research from the basic molecular and cellular principles of
these cells to their involvement in neurological diseases including stroke, Alzheimer's disease, and multiple sclerosis. It includes new chapters on transmitter release from exocytosis from glia, glia derived stem cells, glia and synaptic transmission, glia and axon guidance, an entirely new
section on mechanisms of glial injury, and several new chapters on the roles of glia in different diseases. The new edition was written with both students and experts in mind. It provides a basic introduction to the entire range of glial topics and detailed information with critical assessment of
the research literature. Neuroscience textbooks focus on the properties of neurons, whereas this book fills the information void about the brain's other cells. Neuroglia, Second Edition, is an essential reference source for newcomers, including graduate students, to neuroanatomy, neurochemistry,
neurophysiology, and molecular neurobiology. It is also a vital companion for established researchers in these fields as well as clinicians in neurology, neurosurgery, psychiatry, neuropathology, and neuro-oncology.

624 pages, Hardcover

First published October 19, 1995

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Helmut Kettenmann

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Profile Image for Liam O'Leary.
555 reviews145 followers
October 19, 2018
I didn't read all chapters but I made detailed summary notes on almost all the astrocyte chapters.

As a PhD student studying human astrocytes I am hesitant to recommend this or any textbook, given there haven't yet been enough studies to form a strong consensus about the structural or functional identity of just about any glial cell type.

For example, the astrocyte field currently has many disputes about general principles that are not tackled in this book as they are too new, for example: astrocytic gliotransmission, astrocyte-specific connexins, the function and specificity of astrocyte markers, and the positive or negative role of astrogliosis. Many of the chapters are filled with old 1980 papers studying primary astrocyte (not even a/n) cultures. I did not find many of the papers that I have learned to be critical to my field in the latest ebook and hardcover editions provided by my university and another (for example, by the Molofsky, Barres and Nedergaard groups).

The chapters focusing on the evolution and invertebrate glial systems were the most helpful as that literature rarely comes up in general glial discussion.

But, in short, you would be better off reading reviews if you're a specialist, and not trying if you're not a specialist, because the field is presently moving too fast and controversially for documenting useful take-home messages.
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