Martin Caetano

“You are never dedicated to something you have complete confidence in. No one is fanatically shouting that the sun is going to rise tomorrow. They know it’s going to rise tomorrow. When people are fanatically dedicated to political or religious faiths or any other kinds of dogmas or goals, it’s always because these dogmas or goals are in doubt.”
― Robert M. Pirsig, Zen and the Art of Motorcycle Maintenance

“Sirtuins instruct the histone spooling proteins to bind up DNA tightly, while they leave other regions to flail around. In this way, some genes stay silent, while others can be accessed by DNA-binding transcription factors that turn genes on.12 Accessible genes are said to be in “euchromatin,” while silent genes are in “heterochromatin.” By removing chemical tags on histones, sirtuins help prevent transcription factors from binding to genes, converting euchromatin into heterochromatin.”
― David Sinclair, Lifespan: Why We Age—and Why We Don't Have To

“A waltz, Anna Arkadyevna?" "I don't dance when it's possible not to dance," she said.”
― Leo Tolstoy, Anna Karenina

“Peace of mind isn’t at all superficial, really,” I expound. “It’s the whole thing. That which produces it is good maintenance; that which disturbs it is poor maintenance. What we call workability of the machine is just an objectification of this peace of mind. The ultimate test’s always your own serenity. If you don’t have this when you start and maintain it while you’re working you’re likely to build your personal problems right into the machine itself.”
― Robert M. Pirsig, Zen and the Art of Motorcycle Maintenance