Hit by retarded good creatures that has humorous consequences) (think a parody on midsummer night's dream)
Stuck in a town because of a disease, with the well water as the only "cure"(and have the 'disease' be poison in the food, set by some overly-controlling, concerned old lady. stop the lady, stop the disease.)
Have them go to a castle where the people there are being mind-controlled by the lord of the castle (evil), not realizing it because they slowly lose their free will. Have some of the characters 'lose' themselves to this power, and have to fight it (or have one be immune and wonder why their friends are acting strangely around the lord and do whatever he wants (still cliche)).
have one character get abducted by some random village that thinks of them as either God, sacrifice, or food.
Have one get shot by a 'live' arrow that is going deeper and deeper into that person until they do something.
Have come to take one of them, and have the rest of the group have to go get them back. Or just have that one character try to find a way out of the "netherworld." Or a smattering of the two.
Have the find out she's engaged to some evil/detestable character that she s. Really funny if was married.
Have a character be accused of a crime in a random village.
Have a character be eaten by a rather large creature, only to come out later by cutting themselves out of the gut.
Have a character get possessed by something or "poisoned" by something. This could do many things. get them to join the other side, get them to completely obey someone else, forget everything, make them "fall in love" with someone else (really funny if one was married), someone else (again, really funny if the one d was the spouse), change them into a supposed monster, etc.
Attacked by hired bandits, and have one character be carried away prisoner and then sold as slave. Then there can be side-story that ties into main story about getting them back.
Have ALL of the characters captured and sold into slavery.
Have there be something that is always moving, getting closer with each day.
....etc....Hope that helps, sorry if that was long
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