What was the curse,and who gave it,and why?

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Meri Kim pretty much said it. Elizabeth Woodville and Elizabeth of York cursed the murderer of the princes in the tower. The curse entailed that the person responsible would lose all of their males descendants until only (mostly barren) girls could inherit. I suggest reading the series in order just because each story sheds more light on what happens in The King's Curse. The curse is given in The White Queen. The murderer of the first prince is revealed in The Red Queen. The murderer of the second prince (she basically says outright that the pretender Perkin Warbeck was him) is revealed in The White Princess. Basically Philippa's theory is that the Tudors killed the princes and she's created the curse as a supernatural way to explain why their dynasty died out in the male line and why Henry VIII was the first monarch to have issues with producing an heir.
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Anna I agree with the two previous answers - the curse laid on the king by Elizabeth Woodville. Though technically the curse is laid on the murderer of the princes, so you could interpret the title differently ie how the king curses the country or the Plantagenets under his rule. eg through the Tudor plague - the sweating sickness or his paranoid persecutions. Also if you look in the author's note Gregory adds an interesting aside about Kell's disease (which she doesn't use in the novel).
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by Philippa Gregory (Goodreads Author)
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