Newton’s definitive biographer, Richard Westfall, points out that the program for the work to come was laid down in 1664, when Newton, just twenty-one, was still enrolled at Trinity College. That’s when he first dove into the mathematical inquiries that would dominate his first several months back home, and when he produced an extraordinary series of forty-five queries in which he grappled with fundamental issues of time, matter, motion, and much more.
