In 2000, a landmark paper in the journal Cell listed six attributes in particular that all cancer cells have, namely: They divide without limit. They grow without direction or influence from outside agents like hormones. They engage in angiogenesis, which is to say they trick the body into giving them a blood supply. They disregard any signals to stop growing. They fail to succumb to apoptosis, or programmed cell death. They metastasize, or spread to other parts of the body.

