Antidepressants have been implicated in a number of schoolyard shootings, such as the 1999 Columbine High School massacre, where two students killed twelve of their classmates and a teacher. One of the killers was taking Luvox at the time. Adderall—one of the drugs cited by Cruise—is an amphetamine often prescribed for attention-deficit/hyperactivity disorder; it sometimes causes increased aggression in children and adolescents. Ritalin, the most common drug prescribed for ADHD, is similar to cocaine in its potential for addiction.

