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Chromosome 6

(Jack Stapleton and Laurie Montgomery #3)

3.90  ·  Rating details ·  13,939 ratings  ·  330 reviews
Behind the headlines on cloning--Dr. Robin Cook blends fact with fiction in one of his most terrifying bestsellers...Chromosome 6 is a prophetic thriller that challenges the medical ethics of genetic manipulation and cloning in the jungles of equatorial Africa, where one mistake could bridge the gap between man and ape--and forever change the genetic map of our existence.. ...more
Paperback, 456 pages
Published April 1st 1998 by G.P. Putnam's Sons (first published January 1st 1997)
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Average rating 3.90  · 
Rating details
 ·  13,939 ratings  ·  330 reviews

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Apr 24, 2012 rated it liked it
Shelves: thriller
Interesting topic, exciting storyline. Not my favorite by Cook though. It was okay.
Mansuriah Hassan
Mar 21, 2016 rated it really liked it  ·  review of another edition
This book is the third medical thriller series of Jack Stapleton and Laurie Montgomery. The author Robin Cook is a physician and writer. For those who believe that science and technology can radically change the world for good, this is sort of an eye-opener. The story line starts a bit slow, then becomes quite intriguing in the middle and then leads up to a rather unsatisfactory finish.

Cook develops two parallel and intersecting plots about scientists in Equatorial Guinea who are frantically exp
Jul 06, 2010 rated it it was ok
This book has its pros and cons.

Pros: To anyone who loves the applications of biotechnology to medical fields, and its ethical implications, this book provides a good plot personally, I feel it leaves the reader with the idea that the ethics of such research and practical genetic applications are very real.

Cons: The plot. I mean, in the beginning, I liked how the plot builds in both storylines, and I liked how the story progressed. But the whole idea that a medical examiner from New York would m
Apr 11, 2014 rated it really liked it
Read this in a day, slowish start but picked up. I didn't connect to the characters though, except for Warren. I love his friendship with Jack.
The ending was incredibly unsatisfactory though. Maybe the numerous unanswered questions are answered in a later Robin Cook novel?


You never learn what happened with GenSys, or Kevin, Melanie or Candace. Like... cool, they don't die. But what DO they do? Did Kevin end up hooking up with one of them? (Both?) What happens when Tayl
Jayesh Bhoot
The book starts off with a promising premise of a doctor worrying about his ethically horrifying invention in a darker, deserted part of Africa. Parallel to it, the two famous pathologists - Jack Stapleton and Laurie Montgomery - work on an intriguing, but almost clueless murder of a mobster. These two parallel story lines unfold neatly, intertwining the characters in the process.

Though the investigation of the two pathologists was awesome, it also faltered the pace of the story. Cook stuffed an
John Beta
Jul 31, 2019 rated it liked it
This had my on the edge the whole time with a story of murder, mafia, DNA manipulation, jungle adventure, etc. HOWEVER, what the hell happened to the ending? It was like riding a roller coaster and then the damn thing broke down near the end. I still like this author and will read more, but this ending, or lack thereof was like he realized it was getting a bit long and decided to end the story as economically as possible. Thus, my 3 stars vs. 4.
Austin Mccarthy
Dec 13, 2011 rated it it was amazing
Summary:Chromosome 6 takes place in two totally different main settings. There is a medical office in New York City, but there is also a medical research center, Gensys, in the town of Cogo, Equatorial Guinea, Africa. In this research facility, the scientist are expierimenting with the extraction of the short arm of chromosome six. After extracting the short arm of chromosome six, they would insert it into a bonobo, a ape-like creature that is like humans (DNA wise). This process is used for org ...more
Christina Stathopoulos
Sep 05, 2020 rated it it was amazing
This was my first book by Robin Cook and I really enjoyed it! It is very suspenseful and draws you in well with his style of writing. The book is set between New York City and Equatorial Guinea, following along a story via the perspective of various characters. At first, it took me a little while to get into the book and understand the different characters involved, but I eventually caught on and really enjoyed the story. If you like the idea of a thriller mixed with biomedicine + genetics, then ...more
Shabbeer Hassan
I had always enjoyed Robin Cook's books, but then I gave up on him. His books just got so repetitive and predictable. So it's been a long time, but I decided to give Chromosome 6 a try. This book seemed a bit harder-edged than the other Cook books I'd read, with a very serious theme, and a respectful look at the relevant issues.

There are two related stories going on. One takes place in New York, where a mobster's death takes a strange turn during the autopsy. The investigators stumble onto a rea
Tanaya Deshmukh
Mar 20, 2020 rated it really liked it
This was my first Robin Cook Book. I had heard about it from my father who has read many of his books. One of my friends, being a Robin Cook fan, suggested me to start with this one. I loved the book, the story was fast-paced and I felt like I was on an adventure ride filled with fun and excitement. The book has two medical examiner's Jack Stapleton and Laurie Montgomery. I loved how the women were such badasses in this one. There were points in this book where my heart stopped beating, thinking ...more
Feb 12, 2011 rated it liked it
This was actually a re-read for me. Kevin Marshall is a molecular biologist working in Equatorial Guinea. He is able to manipulate Chromosome 6 of bonobos (ape-like creatures) and replace with human DNA. This allows for humans to create their own organ donors (bonobos) and then the organs are harvested when needed. GenSys is funding this project and they don't really appear to be evil...but their on-site managers are greedy and will do anything to keep the lucrative project going. When Kevin see ...more
Ali Hassan
Jan 03, 2016 rated it it was amazing
This review has been hidden because it contains spoilers. To view it, click here.
Apr 04, 2015 rated it it was amazing
Shelves: thrillers
This fast paced thriller by Robin Cook featuring jack and laurie is my first book in the series. I was quite impressed how the author has woven the story despite the fact that this book being quite technical. I would definitely recommend this book to people as the story is gripping and really interesting. have a look at the glossary behind or have a biology dictionary nearby before you start the book !!! ...more
Mar 04, 2010 rated it liked it  ·  review of another edition
Once again Robin Cook tells us that we shouldn't fool with Mother Nature. There is always just enough possibility in what he is writing about to make you think that yes, somewhere in a lab somewhere, someone is trying to do just this. This one is genetics gone awry.

I have read a lot of Dr. Cook's novels but Coma is still my favorite.
Jul 14, 2013 rated it really liked it
A typical and somewhat predictable thriller and almost science fiction, but with a difference. It is medical research and an evil multinational pitted against those with principles. And of course, those marvellous bonobos. Much of it is set in AFrica with steaming jungles and exotic non-western settings.
Jul 20, 2012 rated it really liked it  ·  review of another edition
In this medical thriller Cook returns us to the characters who work in the NYC morgue. They share the scene with characters at a research complex on the west coast of Africa. In non-stop action, the two stories converge with a harrowing climax. I found the African part totally fascinating.
Oct 06, 2012 rated it really liked it
Shelves: favourites
Chromosome 6 was one of the earliest Si Fi books I read. Robin Cook has done an excellent job here! The very idea of gene transplant which as hitherto a boring chapter in Science text books was suddenly cool and awesome! I thoroughly enjoyed reading the book!!
A thrilling page turner. With a riveting mix of murder, mystery, medical, adventure, action, gangland and science, this book will draw you in and then add a surprising take on genetic engineering that would put any ethics committee in a tizzy.
Patrick Scheele
I did like the mysteries Jack and Laurie were trying to solve. They were appropriately perplexing. But not for the reader! We learn almost immediately what is going on, because we also follow this Kevin guy who knows all about it. So, don't read this book if you like to be kept in the dark as much as the investigators are.

I wasn't particularly fond of the whole "apes with a tiny bit of human DNA are people too" storyline. It was preachy, unbelievably cold that they cared more about the apes than
Varun Varanasy
Aug 17, 2020 rated it really liked it
Been a while since I read anything out of order, but I enjoyed reading this book and piecing together past events. Since I hadn't read the first 2 books, I saw Laurie as this ex-protagonist of "her own series," and I had an entertaining time piecing together everyone's characters. I especially enjoyed painting the sceneries in my mind. Some parts were pretty funky though, with Melanie & Candace popping into Kevin's life; it was a little iffy for me in the beginning, but I got used to it. I somet ...more
May 27, 2019 rated it really liked it
This was actually an assigned summer reading book when I was in high school, but it failed to hook me in the first twenty pages, and has sat abandoned on my shelf for more years than I wish to admit. That is why I didn't realize until I was part way in that it was actually the third book in a series, but I kept going, anyway. It sort of works as a stand-alone, but there are some references to past books that make it obvious that you've missed out on some excitement if you're just jumping into th ...more
Paul Bolton
Jul 22, 2019 rated it liked it
Found this enjoyable but frustrated at times. There is an awful lot in this book and sometimes you are just left to wonder... why? Why? Why? Then also, did that really happen? The good points have to be how the story was told and laid out - in the used style of Cook, that we know and love. However, on the other hand the science in this book is a little high-brow (even comes with an glossary!!!!) and sometimes you can get the feeling of been bogged down and really getting lost. Also, as other rev ...more
Apr 20, 2018 rated it really liked it
Shelves: mystery-suspense
A molecular biologist has discovered a way to move a chromosome on a DNA strand in such a way as to make it possible to do trans species transplants. A corporation seizes upon the idea and starts doing transplants for wealthy clients without the approval of any first world nation. It chooses a very small impoverished country in Africa whose government is happy to see inflow of money regardless of the means.
However our sleuth coroners, Jack Stapleton and Laurie Montgomery, get their hands upon
Deepesh Rammoorthy
Aug 16, 2020 rated it liked it
These medical thrillers keep getting better!
Jack Stapleton and Laurie Montgomery are back in a roller coaster ride chasing the autopsy trail of a murdered gangster all the way from New York to an unknown country in the dense African Jungles, reachable by Atleast three different planes.
A mind boggling discovery awaits them in Africa. organ transplant with an unimaginable playing havoc by reprogramming the human DNA.... As the cover says.... Night mare possibilities of our medic
Antonie De Klerk
Jul 05, 2017 rated it it was ok
The plot is a bit ridiculous. Creating a protohuman from bonabo and human dna just so the rich can have an organ donor on standby... Does the bonobo then have all human organs? How long could a thing like that survive? The creator then sets them free in the jungles of Africa and the reader is supposed to sympathise and approve of this tremendously arrogant and stupid behaviour. Imagine how much havoc that would cause to the indigenous species of the area. Seems quite typical colonial thinking th ...more
Jan 18, 2018 rated it really liked it
This review has been hidden because it contains spoilers. To view it, click here.
Jun 10, 2017 rated it liked it  ·  review of another edition
My last dystopian cloning thriller for now. While it moves along quickly enough, and the science was interesting- there did seem some plot issues. I think it's aged, I wouldn't think a giant illegal biotech corporation would bother having a secret monkey island in Africa to avoid the bad publicity if it was found out - so yes, this book is not dystopian enough! Also I would love a boss who would agree to let me go to Equatorial Guinea for work based on my say so.
Chaitalee Ghosalkar
Jul 19, 2018 rated it liked it
A topic as interesting as transgenic transplants, and you think it can't get any better. With respect to the topic, the book holds your interest right till the end.

If only the same thing could be said about the writing style. Considering that the protagonists and recurring characters of the author's other books are in their late thirties, it is very annoying to see them talk in a childish manner. Also the male lead Jack Stapleton's sense of humor can at best be described as sad.
Priscilla Asir
Aug 08, 2018 rated it it was ok
Just like every other Cook's book. First 50 pages was a drag, after that you wont be able to put the book down.
But I must say i am not very happy with the climax. Though the users are able to assume what must have been happened at the end, it would have been better if Cook was little more narrative and took that little extra effort to say How it all ended and i feel he should have given the reader the pleasure by telling how the Bad guys failed.
Gail Kulp
Jun 04, 2019 rated it liked it
This was the first of this series that I struggled with. There was way too many technical descriptions of scientific procedures and, even with the glossary in the back, it look me a while to really find the story amongst the details. And, the ending seemed rushed with little details on the rest of the characters’ trip and additional details on what happened to the scientific lab and the people responsible. Hoping this is a fluke and the next book with go back to being good.
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Has anyone read this author? 4 7 Dec 25, 2019 08:29AM  
Chromosome 6 1 8 Oct 18, 2015 01:22PM  

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Librarian Note: Not to be confused with British novelist Robin Cook a pseudonym of Robert William Arthur Cook.

Dr. Robin Cook (born May 4, 1940 in New York City, New York) is an American doctor / novelist who writes about medicine, biotechnology, and topics affecting public health.

He is best known for being the author who created the medical-thriller genre by combining medical writing with the thri

Other books in the series

Jack Stapleton and Laurie Montgomery (1 - 10 of 12 books)
  • Blindsight (Jack Stapleton & Laurie Montgomery, #1)
  • Contagion (Jack Stapleton & Laurie Montgomery, #2)
  • Vector (Jack Stapleton & Laurie Montgomery, #4)
  • Marker (Jack Stapleton & Laurie Montgomery, #5)
  • Crisis (Jack Stapleton & Laurie Montgomery, #6)
  • Critical (Jack Stapleton & Laurie Montgomery, #7)
  • Foreign Body (Jack Stapleton & Laurie Montgomery, #8)
  • Intervention (Jack Stapleton & Laurie Montgomery, #9)
  • Cure (Jack Stapleton & Laurie Montgomery, #10)
  • Pandemic (Jack Stapleton & Laurie Montgomery, #11)

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