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The Coenzyme Q10 Phenomenon
How to combat heart disease, mitral valve prolapse, cancer, and much more by supplementing a little-known vitamin-like substance produced by your body.
192 pages, Paperback
First published September 27, 1998
About the author
Stephen T. Sinatra
47 books31 followersSTEPHEN T. SINATRA, M.D., F.A.C.C., F.A.C.N.
is a board-certified cardiologist and certified psychotherapist with more than thirty–five years of clinical experience treating, preventing and reversing heart disease. He also is certified in anti-aging medicine and nutrition. Dr. Sinatra has specialized in integrating conventional medical treatments for heart disease with complementary nutritional, anti-aging, and psychological therapies to help heal the inflammation and plaque processes that cause heart attacks and stroke. He is a Fellow of the American College of Cardiology, an Assistant Clinical Professor of Medicine at the University of Connecticut School of Medicine, and a former chief of cardiology and medical education at Manchester (Connecticut) Memorial Hospital.
A prolific author, Dr. Sinatra has written numerous books, including his current bestseller The Great Cholesterol Myth (Fair Winds Press, 2012), Reverse Heart Disease Now (Wiley, 2008), The Sinatra Solution: Metabolic Cardiology (Basic Health Publications, 3rd ed., 2011), Lower Your Blood Pressure in Eight Weeks (Ballantine Books, 2003), Heart Sense for Women (LifeLine Press, 2000), Heartbreak & Heart Disease (Keats, 1999), and Earthing:The Most Important Health Discovery Ever? (Basic Health Publications, 2010). He is also the host of the Internet’s leading integrative cardiology website for the public, www.heartmdinstitute.com.
is a board-certified cardiologist and certified psychotherapist with more than thirty–five years of clinical experience treating, preventing and reversing heart disease. He also is certified in anti-aging medicine and nutrition. Dr. Sinatra has specialized in integrating conventional medical treatments for heart disease with complementary nutritional, anti-aging, and psychological therapies to help heal the inflammation and plaque processes that cause heart attacks and stroke. He is a Fellow of the American College of Cardiology, an Assistant Clinical Professor of Medicine at the University of Connecticut School of Medicine, and a former chief of cardiology and medical education at Manchester (Connecticut) Memorial Hospital.
A prolific author, Dr. Sinatra has written numerous books, including his current bestseller The Great Cholesterol Myth (Fair Winds Press, 2012), Reverse Heart Disease Now (Wiley, 2008), The Sinatra Solution: Metabolic Cardiology (Basic Health Publications, 3rd ed., 2011), Lower Your Blood Pressure in Eight Weeks (Ballantine Books, 2003), Heart Sense for Women (LifeLine Press, 2000), Heartbreak & Heart Disease (Keats, 1999), and Earthing:The Most Important Health Discovery Ever? (Basic Health Publications, 2010). He is also the host of the Internet’s leading integrative cardiology website for the public, www.heartmdinstitute.com.
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Displaying 1 - 4 of 4 reviews
October 9, 2019
Trusted doctors have told me to use Q10. I do.
***
10/9/19
Found linked article of interest
https://www.sciencedaily.com/releases...
" Since ACADS also uses CoQ10 for dumping electrons, it gives rise to a dilemma, as there is only so much CoQ10 to go around."
How the colon prioritizes gas detox over energy use
Date:
October 7, 2019
Source:
Michigan Medicine - University of Michigan
Summary:
Smelly flatulence is one way our bodies manage our well-being. It turns out expelling noxious gas takes priority in our guts.
"How then does the cell prioritize clearing a poisonous gas over making energy?"
Says Landry, "Sulfide is a byproduct of digestion that our bodies have to continuously contend with. If you have a diet without enough fiber, it could potentially aggravate the effects of hydrogen sulfide or our ability to detoxify it."
***
10/9/19
Found linked article of interest
https://www.sciencedaily.com/releases...
" Since ACADS also uses CoQ10 for dumping electrons, it gives rise to a dilemma, as there is only so much CoQ10 to go around."
How the colon prioritizes gas detox over energy use
Date:
October 7, 2019
Source:
Michigan Medicine - University of Michigan
Summary:
Smelly flatulence is one way our bodies manage our well-being. It turns out expelling noxious gas takes priority in our guts.
"How then does the cell prioritize clearing a poisonous gas over making energy?"
Says Landry, "Sulfide is a byproduct of digestion that our bodies have to continuously contend with. If you have a diet without enough fiber, it could potentially aggravate the effects of hydrogen sulfide or our ability to detoxify it."
March 10, 2012
I bought L carnitine and the heart, The CoQ10 phenomenon and The Sinatra Solution by Dr Stephen T. Sinatra all at once.
I was very impressed by Sinatra's ideas and the way his books are put together. They are very easy to read for laypeople, but also contain very complex and detailed information for those that would like it. There is also a lot of useful information given on dosages and types of supplements and how they differ and which are best and the information is all well referenced.
As it turned out, my buying of the first 2 books was unnecessary, as 'The Sinatra Solution' book is a summary of both of them and also slightly more up to date.
The information in this book is ESSENTIAL for anyone that has M.E., or any other mitochondrial or cardiac or neurological disorder. (As is explained in the HFME paper 'CoQ10 (ubiquinol), L carnitine, D ribose and M.E.'). I can't recommend L carnitine, magnesium and ubiquinol more. I hope patients will look into them and read the facts rather than just rejecting them because they are not yet totally 'mainstream.' This has far more to do with substances like carnitine being unpatentable than any lack of scientific support for these supplements!
'The Sinatra Solution' is an ideal book for patients and also for patients to give to their doctors. I highly recommend it.
Note that ubiquinol is the best form of CoQ10, not ubiquinone - which is inferior.
Jodi Bassett, The Hummingbirds' Foundation for M.E.
I was very impressed by Sinatra's ideas and the way his books are put together. They are very easy to read for laypeople, but also contain very complex and detailed information for those that would like it. There is also a lot of useful information given on dosages and types of supplements and how they differ and which are best and the information is all well referenced.
As it turned out, my buying of the first 2 books was unnecessary, as 'The Sinatra Solution' book is a summary of both of them and also slightly more up to date.
The information in this book is ESSENTIAL for anyone that has M.E., or any other mitochondrial or cardiac or neurological disorder. (As is explained in the HFME paper 'CoQ10 (ubiquinol), L carnitine, D ribose and M.E.'). I can't recommend L carnitine, magnesium and ubiquinol more. I hope patients will look into them and read the facts rather than just rejecting them because they are not yet totally 'mainstream.' This has far more to do with substances like carnitine being unpatentable than any lack of scientific support for these supplements!
'The Sinatra Solution' is an ideal book for patients and also for patients to give to their doctors. I highly recommend it.
Note that ubiquinol is the best form of CoQ10, not ubiquinone - which is inferior.
Jodi Bassett, The Hummingbirds' Foundation for M.E.
October 30, 2025
📖 The Coenzyme Q10 Phenomenon — Stephen T. Sinatra
Poucos autores conseguiram traduzir a complexidade da bioquímica celular com tanta clareza e sensibilidade quanto o cardiologista Stephen T. Sinatra. Neste livro, ele revela o papel fascinante da Coenzima Q10 — uma molécula essencial para a produção de energia mitocondrial e, ao mesmo tempo, um potente antioxidante que protege o coração, o cérebro e todas as células do corpo.
Sinatra não apenas apresenta a Q10 como um suplemento, mas como um verdadeiro elo entre a medicina tradicional e a visão integrativa da saúde. Ele demonstra, com base em décadas de prática clínica e pesquisas científicas, como a deficiência dessa coenzima está ligada à fadiga, à insuficiência cardíaca, à degeneração neurológica e até a distúrbios emocionais relacionados à baixa energia celular.
A leitura é envolvente porque une ciência e humanidade: o autor descreve casos reais de pacientes que recuperaram vitalidade e clareza mental após otimizar seus níveis de Q10 — um testemunho do poder que a energia celular tem sobre o corpo e a mente.
Para quem busca compreender os fundamentos bioquímicos da vitalidade e da longevidade sob uma ótica verdadeiramente integrativa, The Coenzyme Q10 Phenomenon é leitura obrigatória. Ele não fala apenas de um nutriente, mas de um princípio de vida: a restauração da energia como base para a cura.
Poucos autores conseguiram traduzir a complexidade da bioquímica celular com tanta clareza e sensibilidade quanto o cardiologista Stephen T. Sinatra. Neste livro, ele revela o papel fascinante da Coenzima Q10 — uma molécula essencial para a produção de energia mitocondrial e, ao mesmo tempo, um potente antioxidante que protege o coração, o cérebro e todas as células do corpo.
Sinatra não apenas apresenta a Q10 como um suplemento, mas como um verdadeiro elo entre a medicina tradicional e a visão integrativa da saúde. Ele demonstra, com base em décadas de prática clínica e pesquisas científicas, como a deficiência dessa coenzima está ligada à fadiga, à insuficiência cardíaca, à degeneração neurológica e até a distúrbios emocionais relacionados à baixa energia celular.
A leitura é envolvente porque une ciência e humanidade: o autor descreve casos reais de pacientes que recuperaram vitalidade e clareza mental após otimizar seus níveis de Q10 — um testemunho do poder que a energia celular tem sobre o corpo e a mente.
Para quem busca compreender os fundamentos bioquímicos da vitalidade e da longevidade sob uma ótica verdadeiramente integrativa, The Coenzyme Q10 Phenomenon é leitura obrigatória. Ele não fala apenas de um nutriente, mas de um princípio de vida: a restauração da energia como base para a cura.
May 20, 2008
Pretty technical but good for those who like science.
Displaying 1 - 4 of 4 reviews