Goodreads helps you keep track of books you want to read.
Start by marking “Ageless: The New Science of Getting Older Without Getting Old” as Want to Read:
Ageless: The New Science of Getting Older Without Getting Old
Enlarge cover
Rate this book
Clear rating
Open Preview

Ageless: The New Science of Getting Older Without Getting Old

3.84  ·  Rating details ·  712 ratings  ·  117 reviews
With the help of science, could humans find a way to become old without getting elderly, a phenomenon otherwise known as "biological immortality"? In Ageless, Andrew Steele, research fellow at Britain's new and largest biomedical laboratory, the Francis Crick Institute, shows us that the answer lies at the cellular level. He takes us on a journey through the laboratories ...more
Hardcover, 304 pages
Published December 29th 2020 by Doubleday Books
More Details... Edit Details

Friend Reviews

To see what your friends thought of this book, please sign up.

Reader Q&A

To ask other readers questions about Ageless, please sign up.

Be the first to ask a question about Ageless

Community Reviews

Showing 1-30
Average rating 3.84  · 
Rating details
 ·  712 ratings  ·  117 reviews

More filters
Sort order
Start your review of Ageless: The New Science of Getting Older Without Getting Old
Alicia Bayer
Jan 21, 2021 rated it liked it
This is a fascinating book for fellow science geeks, but it's not a book on how the reader is necessarily going to avoid aging. Steele is a scientist who takes us on a deep dive into the 9 reasons he says we age. He maintains that aging is not required and that if we can manipulate cells enough, it may be possible for people to never age in the future. That's the thing though, this is all futuristic stuff. It's all cell manipulation and promising technology. It is quite interesting, but I'm not ...more
Lou (nonfiction fiend)
Dec 24, 2020 rated it it was amazing
Why do we grow old? It’s a universally accepted part of the human experience. The fact that we are not immortal drives many of our decisions, whether conscious or not: do you want to spend your life in one country only? Single, or married? Chasing a career, and if so, in what? But biologists are investigating a different question – why do we age? And, crucially, can we stop it? In Ageless, computational biologist Andrew Steele reveals the science behind the most important biomedical question of ...more
Jan 12, 2021 rated it really liked it  ·  review of another edition
Shelves: health, biology
2nd book for 2021.

Fascinating deep-dive into the study of human ageing and many different medical techniques that are in various stages of development to slow and eventually reverse it.

David Rubenstein
This is a fascinating book about the science behind ageing. The book takes a comprehensive look at research into the reasons why we age. I was particularly struck by how optimistic the author is, that some day the secrets of anti-ageing will be understood and ageing will be a thing of the past. It won't happen overnight. Right now, science is finding certain approaches to extend life--and more importantly, to extend healthy life. As each year passes, perhaps a few hours or days can be added to t ...more
Lewis Franielczyk
Jan 14, 2021 rated it it was amazing
My new goal in life is to become a Galapagos Tortoise.
Mal Warwick
May 12, 2021 rated it liked it  ·  review of another edition
Shelves: nonfiction
If you’re considering this book in hopes of finding some magical supplement or salve to add ten years to your life, forget it. The author is a PhD physicist turned computational biologist—a serious scientist. In Ageless, he relates the latest findings about the emergence of a new field called biogerontology. The word is a mouthful, but its meaning is transparent: it’s the study of the biological basis of aging and age-related diseases. And the author, Dr. Andrew Steele, contends that advances in ...more
Live Forever or Die Trying
Feb 25, 2021 rated it it was amazing
Disclaimer: I was given an ARC of this book by Doubleday Books via NetGalley in exchange for an honest review.

Over the past two years Longevity, Bio-gerontology, or Life Extension has been a pet subject of mine and during that time I have read over 15 books on different aspects of this topic. With that background I can honestly say that Ageless by Andrew Steele is one of the top books on the subject.

What Ageless does exceptionally well over other books in the topic is being able to convey the s
David C Dawson
Jan 30, 2021 rated it it was amazing
I listened to the audiobook of this and recommend it. Andrew Steele's enthusiasm for his topic is infectious, and he's clearly experienced and comfortable at the microphone.
His thesis is fascinating. In brief, 'curing' ageing is a far better bet than spending time trying to cure many of the common diseases of old age such as heart disease, cancer or dementia.
Steele makes a convincing and balanced case. He gives a lot of detail about how our bodies work, how we got to find out how our bodies work
Peter McCluskey
May 23, 2021 rated it it was amazing
The latest book on aging is a bit more ambitious than the previous two that I reviewed, but still rather modest compared to Aubrey de Grey's book that heralded the start of serious attempts at fighting aging.

Ageless is relatively balanced, well-organized, and comprehensive.

Can Aging be Reversed?

Steele presents many hints that age-related health decline can be slowed, or maybe even reversed:

* the existence of organisms that don't age (i.e. their mortality rate is stable or declines with age): nak
Emil O. W. Kirkegaard
Feb 10, 2022 rated it it was amazing
Liked this book a lot more than the David Sinclair one.
Feb 02, 2021 rated it liked it
I have mixed feelings on this one. The author seems very excited about telomeres, and senescent cells and epigenetics. Okay, fair enough, but he has a very biased viewpoint about anti-ageing research that really troubled me. It troubles me that this scientist has such tunnel vision about the potential of these treatments, particularly in the hands of rich and powerful people. While individual human lifespans are lengthening, there is this other little thing called climate change. As it is, we ar ...more
Aug 28, 2021 rated it really liked it
Note that this is primarily NOT a book about how to keep yourself from feeling the effects of ageing, it's about the scientific breakthroughs that are currently being studied that could prevent future generations from ageing. So, still pretty interesting, and the author does a good job breaking down the science for a non scientist like me to read along and not feel hopelessly lost. ...more
Marian Leica
May 08, 2021 rated it really liked it
When you're truly interested in something, you end up reading any book you can find on the topic.
This book is merely a status update on the research for stopping / reversing aging itself.
Philippe  Bogdanoff
Apr 20, 2021 rated it liked it
The book is a bit too scientific for my test.
Too complicated, too difficult to follow
Duane Nickell
Mar 30, 2021 rated it it was amazing
Although I gave this book a five-star rating, I have somewhat mixed feelings about it. First, the writing is excellent, at least in the chapters I understood. The problem for me was that the first two parts of the book were pretty technical. I have a degree in physics but you almost need a degree in chemistry and biology to follow some of the narrative. I'm getting older and I tend to like books that are easy to read. But, the final two chapters made the book worth the price. In the next to last ...more
David Bahry
Jul 13, 2021 rated it really liked it
If you read one book on the biology of ageing, read this one. If you read a few, read this one first. Andrew Steele’s Ageless (2019) is the best nontechnical introduction available.

The chapters are grouped into three sections.

THE FIRST SECTION is an introduction to basic biology of ageing, including demography (what is ageing?—the fact that old have a higher risk of death than the young); evolution (why did ageing evolve?—natural selection cares less about late life, when you’ve already had a fe
Robin Tierney
Aug 10, 2021 rated it really liked it
Hi. This is not a review. Just notes:

Ageless: The New Science of Getting Older Without Getting Old
by Andrew Steele

Dr Andrew Steele is a scientist, writer and campaigner based in London. After a PhD in physics from the University of Oxford, Andrew decided that ageing was the single most important scientific challenge of our time, and switched fields to computational biology. He worked at the Francis Crick Institute, using machine learning to decode our DNA and predict heart attacks using patient
Seng Wee Wong
Jun 16, 2021 rated it it was amazing
I felt like I understood my body a little better after reading this book. Ironically, we still know very little about how the various ageing treatments do to our bodies. For centuries, we have been accepting ageing as the natural path to death and the modern medical advancements are skewed towards treating the symptoms of the illnesses caused by ageing which eventually lead us to death.

The chances of contracting a chronic illness such as cancer, cardiovascular diseases skyrockets after a certai
Jonathan Crabb
Feb 10, 2022 rated it really liked it
I am really happy that I read this book. The overall goal of the book is to walk through the numerous ways that humans could potentially extend both lifespan (how long your body is healthy) and life age. The author is very detailed in his description potentially to the point where there are parts which read like a biology textbook. This is the only negative thing I can say about the book as it may be too complex and long in its explanations for readers who don't read dense non-fiction. Though fo ...more
Jonathan Palfrey
Mar 22, 2021 rated it really liked it  ·  review of another edition
I'm uncertain how to rate this book. On the one hand, it's well written and brings us up to date (in considerable detail!) on the science of aging: what's happening in our bodies as we age, what could be done about it, and what is the current state of research on these methods (in 2020). It also points out usefully that to delay aging (extending youth) would be very valuable in terms of health, because much ill health is age-related, so extending youth much improves general health.

On the other h
Lukas Lovas
Sep 17, 2021 rated it it was amazing
This was a fascinating read. I very much enjoyed the structure here - starting with explanation of the ideology behind the science of aging, explaining the current situation, the past, future projections and pros&cons, then moving on to the actual science, current research and future possibilities.

Being honest, the science went over my head in places and I'm not too proud to admit it. This book is definitely not wishy-washy and it deals in hard science, so I wouldn't mind recommending it even t
Elizabeth Mason Moses
Apr 23, 2021 rated it it was ok
Please do not read this book if you are looking for lifestyle or even bio-hacking ways to live longer and healthier. There's a very little information on exercise and sleep (nothing you don't know) and no information about nutrition and he actually says not to take supplements.

If you are interested in all the current and recent studies on small creatures about the nitty gritty of what drugs and interventions *could* be in the pipeline for altering our bodies to hopefully evade aging sometime in
Apr 13, 2021 rated it liked it
Pretty informative in a decent style. Obviously very biology focussed. Learnt some things that I will probably adapt to my lifestyle although most are pretty common sense
Apr 20, 2021 rated it liked it
Heavy, heavy on the science, @ 90% of the book. Light (about 10%) on actionable tips to stave off the ill effects of aging. Skip the biochemistry unless you're into that sort of thing and proceed to the last sections of the book. ...more
Jan 16, 2022 rated it it was amazing
4.75 to 5.0. Very technical medical terminology makes it a tough read at times but well worth it. Fascinating throughout. Will be curious to see where the science goes over the years!!
Maria LeBerre
May 08, 2022 rated it really liked it
I'm not on board with the goal of stopping aging and becoming semi-immortal, but there's a lot of interesting info about why we age and what can possibly be done to extend our healthy years. ...more
Mar 28, 2021 rated it it was amazing
Very interesting and compelling...
Greg Teal
Apr 03, 2021 rated it it was amazing
Gave me hope.
Lance McNeill
Too speculative

This book is speculative to the point of near uselessness in practical terms. It’s interesting if you want to know about the earliest studies happening related to anti-aging, but there isn’t much that is actionable for today aside from the common sense advice of not smoking, eating a healthy balanced diet and exercising.
Benjamin Rubenstein
This is a thorough book describing the author's stance on why we should look at aging as a disease and the future ways we may treat that disease. It has a bittersweet ending:
(1) The ways the medical community currently tells us to achieve a longer health- and life-span are all the existing (proven) ways to do so--meaning, there is nothing else we can do, so we can stop beating ourselves up for not doing this or that (so long as we don't smoke, move our bodies, etc.).
(2) At the same time, it's
« previous 1 3 4 next »
There are no discussion topics on this book yet. Be the first to start one »

Readers also enjoyed

  • Age Later: Secrets of the Healthiest, Sharpest Centenarians
  • Think Like a Monk: Train Your Mind for Peace and Purpose Every Day
  • On the House: A Washington Memoir
  • Liftoff: Elon Musk and the Desperate Early Days That Launched SpaceX
  • Exercised: Why Something We Never Evolved to Do Is Healthy and Rewarding
  • The Bone Season (The Bone Season, #1)
  • Ikigai: The Japanese Secret to a Long and Happy Life / The Little Book of Lykke / Lagom: The Swedish Art of Balanced Living
  • Honeybee
  • On Death and Dying
  • The Good Country Equation: How We Can Repair the World in One Generation
  • Troy
  • The Case for Keto: Rethinking Weight Control and the Science and Practice of Low-Carb/High-Fat Eating
  • White Guilt: How Blacks and Whites Together Destroyed the Promise of the Civil Rights Era
  • The Other Passenger
  • On the Shortness of Life
  • Strangers
  • Dreyer's English: An Utterly Correct Guide to Clarity and Style
  • The Empathy Diaries: A Memoir
See similar books…
See top shelves…
Dr Andrew Steele is a scientist, writer and campaigner based in London. After a PhD in physics from the University of Oxford, Andrew decided that ageing was the single most important scientific challenge of our time, and switched fields to computational biology. He worked at the Francis Crick Institute, using machine learning to decode our DNA and predict heart attacks using patients’ NHS medical ...more

News & Interviews

Judging by early reviews and general pop-culture impact, Emily St. John Mandel (Station Eleven) has hit a home run with her latest novel, Sea...
29 likes · 7 comments
“The first, originally published in 2002 and boldly entitled “Strategies for Engineered Negligible Senescence” (SENS for short), was devised by maverick biogerontologist Aubrey de Grey. In its current form, SENS identifies seven differences between old bodies and young which de Grey suggests are the fundamental causes of aging.” 0 likes
“The second, published in 2013, is “The Hallmarks of Aging,” and enumerates nine changes which fit three criteria. First, they need to increase with age: if they don’t, how could they be causing aging? Second, accelerating a hallmark’s progress should accelerate aging, and, third, slowing one should improve it—these two criteria are an attempt to separate things which are merely associated with aging from things that are actually contributing to it. Finally, these hallmarks also come with suggested interventions which could slow or reverse their progression, thus slowing or reversing that aspect of aging, and hopefully putting the brakes on the process overall.” 0 likes
More quotes…