This edition of this highly acclaimed text provides a solid background in medical microbiology including virology and parasitology. Completely revised and updated, this comprehensive, illustrated text has been expanded to include coverage of immunopathology of infectious diseases, gene therapy in immunodeficiency disorders, virulence factors of bacteria, viral pathogenesis, diagnostic virology, and chemotherapeutic agents in virology. Current concepts of lymphocyte activation, transmembrane signaling molecules and intracellular signalling, and t-cell activation are also examined. Chapters covering AIDS, HIV and retroviruses, oncogenes and cancer have also been updated. New clinical vignettes illustrate the principles of microbiology as seen in clinical situations.