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Mitochondria and the Future of Medicine: The Key to Understanding Disease, Chronic Illness, Aging, and Life Itself

4.29  ·  Rating details ·  297 ratings  ·  32 reviews

With information for patients and practitioners on optimizing mitochondrial function for greater health and longevity

Why do we age? Why does cancer develop? What's the connection between heart failure and Alzheimer's disease, or infertility and hearing loss? Can we extend lifespan, and if so, how? What is the Exercise Paradox? Why do antioxidant supplements sometimes d

Kindle Edition, 272 pages
Published February 19th 2018 by Chelsea Green Publishing
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Average rating 4.29  · 
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Apr 10, 2020 rated it it was amazing
Extremely fun and informative book, especially if you are into mitochondria, cellular biology and healthy living, supported not by wishful thinking or conjectures but scientific studies.
A worthy follow-up read to Power, Sex, Suicide: Mitochondria and the Meaning of Life.
Feb 02, 2018 rated it it was amazing  ·  review of another edition
Shelves: netgalley, keepers
Not much that I can say other than, read this book, all of you. The first 40 or so pages, I was questioning my ability to understand the biology/physiology that was being spelled out, but I persisted and it was worth it. I was able to follow it all after I focused and I learned A LOT.

Basically most of our health issues stem or are made worse by our mitochondria not being happy, due to over-eating, toxins from the environment, not enough exercise, etc. Most of these diseases that result from unh
Bruce Perry
Sep 08, 2019 rated it it was amazing
Excellent, readable review of the science behind mitochondria, which exist in most cells of the body (skeletal muscle, heart, brain, major arteries, etc.), contain their own DNA, and generate the energy you live on (bioenergetics). This book is good for students, especially pre-med, because when you become a physician, you will be (hopefully) much more inclined to prescribe exercise and other alternatives like CBD oil, than Big Pharma meds. The book is also easy to grasp for avid, casual science ...more
Jess Macallan
Jan 30, 2018 rated it it was amazing  ·  review of another edition
Shelves: nutrition-health
This book is a well-researched, evidence-based look at the role of mitochondria and the relationship to overall health. The author spends a lot of necessary time outlining the science, and I'd encourage readers to take their time reading through the information presented because it's explained so thoroughly. This is a book I'd highly recommend to functional medicine and integrative practitioners as it outlines the potential roles of supplements and nutrition.

While the author acknowledges he bare
Radosław Magiera
May 30, 2020 rated it it was amazing  ·  review of another edition
Shelves: eee
Książka Mądre mitochondria. Jak opóźnić procesy starzenia i żyć zdrowiej autorstwa Lee Know, kanadyjskiego licencjonowanego naturopaty, była na mojej liście must read od momentu, kiedy się o niej pierwszy raz dowiedziałem. Niestety w tej kategorii jest też sporo innych rzeczy oczekujących na moje zmiłowanie, więc tak sobie i Mitochondria czekały. Gdybym wcześniej spojrzał na tytuł oryginału, który znacząco różni się od polskiej wersji językowej, prawdopodobnie już dawno bym się za tę książkę zab ...more
Mar 08, 2019 rated it really liked it
Not too actionable but has a good overview of Mitochondria. Seems to have 90%+ of the same content as his last book. He literally uses the same theme/examples as in his previous book. I would've thought a bit more diligence would have been merited to at least make this appear like new material (though it looks like he added a few new buzzy supplements). ...more
Mar 23, 2018 rated it really liked it
If you're interested in health and longevity, this book provides a good overview of the role that mitochondria play and how we might be able to improve our health by supporting our mitochondria with lifestyle changes and nutritional supplements. It's fairly technical and probably a tough read if you don't have at least some background in biology, but most of the terms you'll need to know are carefully explained in the text as well as the glossary. The author strays a bit off topic occasionally ( ...more
Mihail Nedkov
Mar 11, 2019 rated it did not like it
1) Too technical without offering anything new or ground-breaking. Same stuff can be read in any Biology textbook.

2) The references make up about 25% of the book and they are clumped together at its back. In other words, when the auther mentions something, there's no citation in the text - neither name;year, nor [number]. So it's practically impossible to figure out with statements connects to which reference.

3) The practical part of the book is really short and the recommendations are super tig
Thyme Wisper
Oct 29, 2018 rated it it was amazing
Both technical and inspiring

What a read! So much information for how we have energy (or don't), and the REAL CAUSES of chronic diseases and aging. AND what we can DO with this information to improve our health, prevent or resolve chronic disease and increase quality of aging.
Sources of research are extensive in the references section. Much of it is still ongoing!
I have already been in nutritional ketosis for almost two years, but I will be tweaking my approach after reading this. Carnivory is no
Karen Selick
Aug 28, 2018 rated it it was amazing
This excellent book explains how the mitochondria work, what illnesses manifest themselves when the mitochondria malfunction, and what supplements you can take to restore the proper functioning of your mitochondria.

This information is available elsewhere, but you have to dig for it. In this book, it's all collected in one place.

After reading this, you will understand the importance of coenzyme Q10, alpha-lipoic acid, l-carnitine, and other nutrients. You'll also understand precisely why a sede
Lauren Butler
May 14, 2018 rated it liked it
Incredibly interesting if you have a strong basis in science or medicine. I came away with the conclusion that mitochondria and energy production are indeed important for just about all health aspects, but was overwhelmed by the number of lifestyle recommendations, supplements, etc.- too many to take into account. Unfortunately, references are clumped together by chapter so there is no way to read more when you have a question about a specific sentence or claim.
Sep 18, 2018 rated it it was amazing
Very very interesting to me plus the author makes reading it not a boring drag but rather fun.

Great book on the topic of health on the most fundamental (cell) level.
May 12, 2018 rated it it was amazing
Easy and short read with lots of useful scientific information for implementing a variety anti-aging strategies focused on mitochondrial health.
Michael Payne
Dec 27, 2020 rated it really liked it
Know thine self: We have evolved and coexist with this "force" inside of us. The better we understand this symbiote that is our mitochondria the more we can an understand ourselves.

The mitochondrial theory of aging, is the leading explanation that best describes what is happening as we age with an observed decline in mitochondrial function.

Inside the trillions of cells that compose you (and all other living things including plants) the mitochondria are said to be the powerhouse of our cells as t
Jan 01, 2019 rated it it was ok
Shelves: health-nutrition
I was very disappointed with this book. Maybe my expectations were too high? I did learn some things, thus the three stars but I felt, most of the book, that he was trying to convince himself that evolution was true. My degree is in science, so even though I believe in Creation according to the Bible, I am very used to wading through the evolution theories in science books. However, I don't want to spend most of the book reading about what I have already waded through many times to glean only a ...more
May 07, 2019 rated it really liked it
A great informative book if you are concerned about your health, the energy your body produces (or isn't) and your longevity. I went with 4 stars only because many might find this book overly scientific, but it definitely is necessary to describe the processes of our body in order to understand how our energy systems work. With that, and re-reading a few pages, it is a wealth of information on what happens with our energy as we age, diseases that are and can be related to the depletion of energy ...more
Jill Bowman
Nov 06, 2019 rated it it was amazing
A very interesting and readable book. That 5th Star was for writing it in such a way that I was able to understand it. At first (I’m thankful I wasn’t studying this for an exam!) I got all of the ETC, ATP, ADP, etc a bit confused... but then Know suggested I look up oxidative polymerase (?) on YouTube. YouTube became my friend for several pages.
It ended up being VERY understandable and interesting. Because I had it on an e reader from the library I didn’t realize that there are several pages of
Mar 06, 2021 rated it liked it
Very, very technical. I listened to it on audiobook and most of the technical details flew by. This is probably one that it would be helpful to have in print. Also it would help to have a background in biochemistry. I did get the important takeaway that you should supplement coq10 though, and I will definitely do that, along with aerobic exercise.
Stephen Burks
Jan 26, 2021 rated it it was amazing
Fighting The Disease Of Aging

This really helped me understand the Mitochondria and apply a holistic approach to create a regimen. I am on my sixth week of crafting a program of recommended supplements, HIIT training, weights, and I contracted COVID-19 at 62 and my immune system was so supercharged my symptoms were mild. Great book I feel fantastic.
Ravinder  B Reddy
Feb 13, 2021 rated it it was amazing
As medical students, we used to find the functioning of mitochondria to be daunting and very complex!
The author, Lee Know, has done an exceptional job in explaining the complex functions of mitochondria, in a simple, vivid and in the most clear way!
This is one of the best science-books that I have read!
Alberto Hoyos
Mar 14, 2020 rated it it was amazing
Mitochondria an the future of medicine

Really good messages about health and our individual capabilities to drive our wellness self improvement
Need previous medicine or biochemical knowledge for better understanding
silvia gracuela fittipaldi
Dec 28, 2018 rated it it was amazing
Mitocondrias y el futuro de la medicina

Su Nivel científico es excelente siendo que el tema requiere profundidad y gran conocimiento.
Nos sumerge en el interior celular en el criterio de la energía . Del Sol al Hombre!
Oct 21, 2020 rated it it was amazing
Shelves: 2020
Great read. Really informative, interesting and De Know sure knows how to keep it fun and entertaining. Already using the information in my practice. I will reference this book for a long time.
Thank you!
Uroš Mikolič
Apr 01, 2021 rated it it was amazing
A very heavy load of knowledge. :)
Marcus Goncalves
Well written and useful for the understanding of mitochondria and how the health of mitochondria impacts us.
Mar 04, 2021 rated it really liked it
Very knowledgeable thorough summary of the numerous benefits of focusing on metabolic health.
Jun 08, 2020 rated it it was amazing
Great read.

Start of the book very detailed, recommend reading over it twice, learnt alot. Buy the book find out for yourself
Luis A
Feb 13, 2020 rated it really liked it
Shelves: to-read-personal
Fascinating information on mitochondria's role in health and longevity. A bit too technical for me though, reason why I didn't go for 5 stars. But highly recommended! ...more
Oct 18, 2020 rated it it was amazing
Shelves: zdrowie
Packed with knowledge about how cells produce energy that makes them live, grow, and die.
Main learning: consume fewer calories
Jonathan Roseland
Apr 06, 2019 rated it really liked it
State of the Art Mitochondrial Research
This book is a concise look at the current mitochondrial science and research findings. If you spend much time browsing mitochondrial studies on Pubmed read this book. It's a little drier and less applicable than for example, Dave Asprey's Head Strong. Good reading for those really into the science. Take your CoQ10 guys!
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