This volume brings together a wealth of data on the neurochemistry and neuropharmacology of schizophrenia. It provides investigators of the etiology of schizophrenia with a basis to formulate future directions. A major portion of the book is devoted to an analysis of the dopamine neurotransmitter system in recognition of the fact that it may represent the most likely site for neurochemical abnormalities to be found in schizophrenia. Developments in the pharmacologic treatment of schizophrenia are dealt with in six authoritative reviews and the advances detailed therein may set the stage for a second generation of improved antipsychotic medications.