Sean is a man searching for meaning in his life. A backpacker from Canada, he is depressed following a break-up with a woman he loved, and realizes he needs to find happiness from within. To do this, he takes an extraordinary (and brave, at least to me) journey alone into the Amazon. At the beginning of the book, he arrives in Lima, where he has some fairly wild days, a few days he feels he needs to have before he begins the journey into the Amazon to learn under the tutelage of a shaman, and before he begins the strict cleansing diet required to take what is called the Ayahuasca treatment, done during a very old and sacred ceremony. The Lima portion is interesting, but the book really takes off when he is finally with Otillia, his guide through the multiple ceremonies he attends. The effects of the Ayahuasca are different for everyone, but in the beginning, they are always bad as the body begins ridding itself of the remnants of years of bodily abuse (sugar, refined foods, fats, smoking, drugs....whatever the person has done). I loved this book, start to finish. I felt every emotion that Sean felt, and his writing style is simply "real". He doesn't cut himself any slack about how he abused his body, mostly with alcohol and drugs. I would love to see a sequel to this book.