Carl-Wilhelm Reinhold de Boor is a German-American mathematician and professor emeritus at the University of Wisconsin–Madison.
Having earned only a high school diploma after 3 and a half years of study at Hamburg University, de Boor entered Harvard as a graduate student of mathematics. After working for a year as a research assistant to Garrett Birkhoff, he went to work for General Motors Research in Warren, Michigan, where he met splines. He received his first postgraduate degree, a Ph.D. from the University of Michigan, in 1966, and then became an assistant professor at Purdue University. In 1972, he accepted a position as professor of mathematics and computer science at the University of Wisconsin–Madison, working out of the UW's Army Math Research Center, which had recently been bombed in opposition to the Vietnam War.